Effect of 3′UTR RET Variants on RET mRNA Secondary Structure and Disease Presentation in Medullary Thyroid Carcinoma

Lucieli Ceolin; Mirian Romitti; Débora Rodrigues Siqueira; Carla Vaz Ferreira; Jessica Oliboni Scapineli; Beatriz Assis-Brazil; Rodolfo Vieira Maximiano; Tauanne Dias Amarante; Miriam Celi de Souza Nunes; Gerald Weber; Ana Luiza Maia

doi:10.1371/journal.pone.0147840

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Peer-reviewed

Research Article

Effect of 3′UTR RET Variants on RET mRNA Secondary Structure and Disease Presentation in Medullary Thyroid Carcinoma

Lucieli Ceolin,

Affiliation Thyroid Section, Endocrine Division, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil
⨯
Mirian Romitti,

Affiliation Thyroid Section, Endocrine Division, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil
⨯
Débora Rodrigues Siqueira,

Affiliation Thyroid Section, Endocrine Division, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil
⨯
Carla Vaz Ferreira,

Affiliation Thyroid Section, Endocrine Division, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil
⨯
Jessica Oliboni Scapineli,

Affiliation Thyroid Section, Endocrine Division, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil
⨯
Beatriz Assis-Brazil,

Affiliation Pathology Department, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
⨯
Rodolfo Vieira Maximiano,

Affiliation Department of Physics, Computational Biophysics Group, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
⨯
Tauanne Dias Amarante,

Affiliation Department of Physics, Computational Biophysics Group, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
⨯
Miriam Celi de Souza Nunes,

Affiliation Department of Physics, Computational Biophysics Group, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
⨯
Gerald Weber,

Affiliation Department of Physics, Computational Biophysics Group, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
⨯
Ana Luiza Maia

* E-mail: almaia@ufrgs.br

Affiliation Thyroid Section, Endocrine Division, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil
⨯

Effect of 3′UTR RET Variants on RET mRNA Secondary Structure and Disease Presentation in Medullary Thyroid Carcinoma

Lucieli Ceolin,
Mirian Romitti,
Débora Rodrigues Siqueira,
Carla Vaz Ferreira,
Jessica Oliboni Scapineli,
Beatriz Assis-Brazil,
Rodolfo Vieira Maximiano,
Tauanne Dias Amarante,
Miriam Celi de Souza Nunes,
Gerald Weber

Published: February 1, 2016
https://doi.org/10.1371/journal.pone.0147840

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Haplotypes
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3' UTR
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RNA structure
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