On the Utility of Short Echo Time (TE) Single Voxel 1H–MRS in Non–Invasive Detection of 2–Hydroxyglutarate (2HG); Challenges and Potential Improvement Illustrated with Animal Models Using MRUI and LCModel

• Hwon Heo ,

  Contributed equally to this work with: Hwon Heo, Sungjin Kim, Hyeong Hun Lee, Hye Rim Cho

  Affiliation Department of Biomedical Sciences, Seoul National University, Seoul, Korea

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• Sungjin Kim ,

  Contributed equally to this work with: Hwon Heo, Sungjin Kim, Hyeong Hun Lee, Hye Rim Cho

  Affiliation Department of Biomedical Sciences, Seoul National University, Seoul, Korea

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• Hyeong Hun Lee ,

  Contributed equally to this work with: Hwon Heo, Sungjin Kim, Hyeong Hun Lee, Hye Rim Cho

  Affiliation Department of Biomedical Sciences, Seoul National University, Seoul, Korea

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• Hye Rim Cho ,

  Contributed equally to this work with: Hwon Heo, Sungjin Kim, Hyeong Hun Lee, Hye Rim Cho

  Affiliation Department of Radiology, Seoul National University Hospital, Seoul, Korea

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• Wen Jun Xu,

  Affiliation College of Pharmacy, Natural Product Research Institute, Seoul National University, Seoul, Korea

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• Se-Hoon Lee,

  Affiliation Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea

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• Chul-Kee Park,

  Affiliation Department of Neurosurgery, Seoul National University Hospital, Seoul, Korea

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• Sunghyouk Park,

  Affiliation College of Pharmacy, Natural Product Research Institute, Seoul National University, Seoul, Korea

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• Seung Hong Choi ,

  * E-mail: hyeonjinkim@snu.ac.kr (HK); verocay1@snu.ac.kr (SHC)

  Affiliations Department of Radiology, Seoul National University Hospital, Seoul, Korea, Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea

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• Hyeonjin Kim

  * E-mail: hyeonjinkim@snu.ac.kr (HK); verocay1@snu.ac.kr (SHC)

  Affiliations Department of Biomedical Sciences, Seoul National University, Seoul, Korea, Department of Radiology, Seoul National University Hospital, Seoul, Korea, Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea

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