Azilsartan Improves Salt Sensitivity by Modulating the Proximal Tubular Na+-H+ Exchanger-3 in Mice

Masaki Hatanaka; Jun-Ya Kaimori; Satoko Yamamoto; Isao Matsui; Takayuki Hamano; Yoshitsugu Takabatake; Carolyn M. Ecelbarger; Shiro Takahara; Yoshitaka Isaka; Hiromi Rakugi

doi:10.1371/journal.pone.0147786

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Open Access

Peer-reviewed

Research Article

Azilsartan Improves Salt Sensitivity by Modulating the Proximal Tubular Na⁺-H⁺ Exchanger-3 in Mice

Masaki Hatanaka,

Affiliation Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Jun-Ya Kaimori ,

* E-mail: kaimori@kid.med.osaka-u.ac.jp

Affiliations Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, Department of Advanced Technology for Transplantation, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Satoko Yamamoto,

Affiliation Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Isao Matsui,

Affiliation Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Takayuki Hamano,

Affiliations Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, Department of Comprehensive Kidney Disease Research, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Yoshitsugu Takabatake,

Affiliation Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Carolyn M. Ecelbarger,

Affiliation Department of Medicine, Division of Endocrinology and Metabolism, Georgetown University, Washington D.C., United States of America
⨯
Shiro Takahara,

Affiliation Department of Advanced Technology for Transplantation, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Yoshitaka Isaka,

Affiliation Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Hiromi Rakugi

Affiliation Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯

Azilsartan Improves Salt Sensitivity by Modulating the Proximal Tubular Na⁺-H⁺ Exchanger-3 in Mice

Masaki Hatanaka,
Jun-Ya Kaimori,
Satoko Yamamoto,
Isao Matsui,
Takayuki Hamano,
Yoshitsugu Takabatake,
Carolyn M. Ecelbarger,
Shiro Takahara,
Yoshitaka Isaka,
Hiromi Rakugi

Published: January 25, 2016
https://doi.org/10.1371/journal.pone.0147786

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