One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4⁺ T Cells, and IL-17A

• Francesca Mancini,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliations Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy, Department of Biomedical Sciences, University of Padua, Padua, Italy

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• Elisabetta Monaci,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Giuseppe Lofano,

  Current address: Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

  Affiliations Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy, Department of Biology and Biotechnologies “Charles Darwin”, University of Rome “La Sapienza”, Rome, Italy

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• Antonina Torre,

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Marta Bacconi,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliations Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy, Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy

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• Simona Tavarini,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Chiara Sammicheli,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Letizia Arcidiacono,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Bruno Galletti,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Donatello Laera,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Michele Pallaoro,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Giovanna Tuscano,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Maria Rita Fontana,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Giuliano Bensi,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Guido Grandi,

  Current address: Centre for Integrative Biology, University of Trento, Trento, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Silvia Rossi-Paccani,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Sandra Nuti,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Rino Rappuoli,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Ennio De Gregorio,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Fabio Bagnoli,

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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• Elisabetta Soldaini ,

  * E-mail: elisabetta.x.soldaini@gsk.com

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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•  [ ... ],
• Sylvie Bertholet

  Current address: GlaxoSmithKline Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines and Diagnostics, S.r.l., Research Center, Siena, Italy

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