Transcriptional Profiling the 150 kb Linear Megaplasmid of Borrelia turicatae Suggests a Role in Vector Colonization and Initiating Mammalian Infection

Hannah K. Wilder; Sandra J. Raffel; Alan G. Barbour; Stephen F. Porcella; Daniel E. Sturdevant; Benjamin Vaisvil; Vinayak Kapatral; Daniel P. Schmitt; Tom G. Schwan; Job E. Lopez

doi:10.1371/journal.pone.0147707

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Peer-reviewed

Research Article

Transcriptional Profiling the 150 kb Linear Megaplasmid of Borrelia turicatae Suggests a Role in Vector Colonization and Initiating Mammalian Infection

Hannah K. Wilder,

Affiliation Department of Pediatrics, Section of Tropical Medicine, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America
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Sandra J. Raffel,

Affiliation Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America
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Alan G. Barbour,

Affiliation Departments of Microbiology & Molecular Genetics, Medicine, and Ecology and Evolutionary Biology, University of California Irvine, Irvine, California, United States of America
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Stephen F. Porcella,

Affiliation Genomics Unit, Research Technologies Section, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America
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Daniel E. Sturdevant,

Affiliation Genomics Unit, Research Technologies Section, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America
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Benjamin Vaisvil,

Affiliation Igenbio, Inc., Chicago, IL, United States of America
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Vinayak Kapatral,

Affiliation Igenbio, Inc., Chicago, IL, United States of America
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Daniel P. Schmitt,

Affiliation Igenbio, Inc., Chicago, IL, United States of America
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Tom G. Schwan,

Affiliation Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America
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Job E. Lopez

* E-mail: job.lopez@bcm.edu

Affiliations Department of Pediatrics, Section of Tropical Medicine, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States of America
⨯

Transcriptional Profiling the 150 kb Linear Megaplasmid of Borrelia turicatae Suggests a Role in Vector Colonization and Initiating Mammalian Infection

Hannah K. Wilder,
Sandra J. Raffel,
Alan G. Barbour,
Stephen F. Porcella,
Daniel E. Sturdevant,
Benjamin Vaisvil,
Vinayak Kapatral,
Daniel P. Schmitt,
Tom G. Schwan,
Job E. Lopez

Published: February 4, 2016
https://doi.org/10.1371/journal.pone.0147707

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