Positive Selection or Free to Vary? Assessing the Functional Significance of Sequence Change Using Molecular Dynamics

• Jane R. Allison ,

  * E-mail: j.allison@massey.ac.nz (JA); anthony.poole@canterbury.ac.nz (AP)

  Affiliations Centre for Theoretical Chemistry and Physics & Institute of Natural and Mathematical Sciences, Massey University Albany, Auckland, New Zealand, Biomolecular Interaction Centre, University of Canterbury, Christchurch, New Zealand, Maurice Wilkins Centre for Molecular Biodiscovery, Massey University Albany, Auckland, New Zealand

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• Marcus Lechner,

  Affiliation Department of Pharmaceutical Chemistry, Philipps-University Marburg, Marburg, Germany

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• Marc P. Hoeppner,

  Affiliation Christian-Albrechts-University of Kiel, Institute of Clinical Molecular Biology, Kiel, Germany

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• Anthony M. Poole

  * E-mail: j.allison@massey.ac.nz (JA); anthony.poole@canterbury.ac.nz (AP)

  Affiliations Biomolecular Interaction Centre, University of Canterbury, Christchurch, New Zealand, School of Biological Sciences, University of Canterbury, Christchurch, New Zealand

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