Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It

Dong-Ki Kim; Hosoon Choi; Hidetaka Nishida; Joo Youn Oh; Carl Gregory; Ryang Hwa Lee; Ji Min Yu; Jun Watanabe; Su Yeon An; Thomas J. Bartosh; Darwin J. Prockop

doi:10.1371/journal.pone.0147553

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Peer-reviewed

Research Article

Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It

Dong-Ki Kim,

Affiliation Institute for Regenerative Medicine, Texas A&M Health Science Center, College of Medicine at Scott and White, Temple, Texas, United States of America
⨯
Hosoon Choi,

Affiliation Institute for Regenerative Medicine, Texas A&M Health Science Center, College of Medicine at Scott and White, Temple, Texas, United States of America
⨯
Hidetaka Nishida,

Affiliation Institute for Regenerative Medicine, Texas A&M Health Science Center, College of Medicine at Scott and White, Temple, Texas, United States of America
⨯
Joo Youn Oh,

Current address: Department of Ophthalmology, Seoul National University Hospital, Daehak-ro, Jongno-gu, Seoul, Republic of Korea

Affiliation Institute for Regenerative Medicine, Texas A&M Health Science Center, College of Medicine at Scott and White, Temple, Texas, United States of America
⨯
Carl Gregory,

Affiliation Institute for Regenerative Medicine, Texas A&M Health Science Center, College of Medicine at Scott and White, Temple, Texas, United States of America
⨯
Ryang Hwa Lee,

Affiliation Institute for Regenerative Medicine, Texas A&M Health Science Center, College of Medicine at Scott and White, Temple, Texas, United States of America
⨯
Ji Min Yu,

Current address: Department of Translational Research, CHA Bio & Diostech Co., Ltd. Yeoksam dong, Gangnam gu, Republic of Korea

Affiliation Institute for Regenerative Medicine, Texas A&M Health Science Center, College of Medicine at Scott and White, Temple, Texas, United States of America
⨯
Jun Watanabe,

Current address: Department of Anatomy, Showa University School of Medicine, Hatanodai, Shinakawa-ku, Tokyo, Japan

Affiliation Institute for Regenerative Medicine, Texas A&M Health Science Center, College of Medicine at Scott and White, Temple, Texas, United States of America
⨯
Su Yeon An,

Affiliation Institute for Regenerative Medicine, Texas A&M Health Science Center, College of Medicine at Scott and White, Temple, Texas, United States of America
⨯
Thomas J. Bartosh,

Affiliation Institute for Regenerative Medicine, Texas A&M Health Science Center, College of Medicine at Scott and White, Temple, Texas, United States of America
⨯
Darwin J. Prockop

* E-mail: Prockop@medicine.tamhsc.edu

Affiliation Institute for Regenerative Medicine, Texas A&M Health Science Center, College of Medicine at Scott and White, Temple, Texas, United States of America
⨯

Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It

Dong-Ki Kim,
Hosoon Choi,
Hidetaka Nishida,
Joo Youn Oh,
Carl Gregory,
Ryang Hwa Lee,
Ji Min Yu,
Jun Watanabe,
Su Yeon An,
Thomas J. Bartosh

Published: January 21, 2016
https://doi.org/10.1371/journal.pone.0147553

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