Transcriptomic Profile of Whole Blood Cells from Elderly Subjects Fed Probiotic Bacteria Lactobacillus rhamnosus GG ATCC 53103 (LGG) in a Phase I Open Label Study

Gloria Solano-Aguilar; Aleksey Molokin; Christine Botelho; Anne-Maria Fiorino; Bryan Vinyard; Robert Li; Celine Chen; Joseph Urban Jr.; Harry Dawson; Irina Andreyeva; Miriam Haverkamp; Patricia L. Hibberd

doi:10.1371/journal.pone.0147426

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Open Access

Peer-reviewed

Research Article

Transcriptomic Profile of Whole Blood Cells from Elderly Subjects Fed Probiotic Bacteria Lactobacillus rhamnosus GG ATCC 53103 (LGG) in a Phase I Open Label Study

Gloria Solano-Aguilar ,

* E-mail: Gloria.SolanoAguilar@ars.usda.gov

Affiliation Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland, United States of America
⨯
Aleksey Molokin,

Affiliation Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland, United States of America
⨯
Christine Botelho,

Affiliation Division of Global Health, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
Anne-Maria Fiorino,

Affiliation Division of Global Health, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
Bryan Vinyard,

Affiliation Statistics Group, Northeast Area, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland, United States of America
⨯
Robert Li,

Affiliation Animal Genomics and Improvement Laboratory, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland, United States of America
⨯
Celine Chen,

Affiliation Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland, United States of America
⨯
Joseph Urban Jr.,

Affiliation Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland, United States of America
⨯
Harry Dawson,

Affiliation Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland, United States of America
⨯
Irina Andreyeva,

Affiliation Division of Global Health, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
Miriam Haverkamp,

Affiliation Division of Global Health, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
Patricia L. Hibberd

Affiliation Division of Global Health, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯

Transcriptomic Profile of Whole Blood Cells from Elderly Subjects Fed Probiotic Bacteria Lactobacillus rhamnosus GG ATCC 53103 (LGG) in a Phase I Open Label Study

Gloria Solano-Aguilar,
Aleksey Molokin,
Christine Botelho,
Anne-Maria Fiorino,
Bryan Vinyard,
Robert Li,
Celine Chen,
Joseph Urban Jr.,
Harry Dawson,
Irina Andreyeva

Published: February 9, 2016
https://doi.org/10.1371/journal.pone.0147426

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Cytoplasm
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Gene expression
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Lactobacillus
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RNA sequencing
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Transcriptome analysis
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Cell membranes
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