Chromosome Bridges Maintain Kinetochore-Microtubule Attachment throughout Mitosis and Rarely Break during Anaphase

Judit Pampalona; Emanuele Roscioli; William T. Silkworth; Brent Bowden; Anna Genescà; Laura Tusell; Daniela Cimini

doi:10.1371/journal.pone.0147420

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Peer-reviewed

Research Article

Chromosome Bridges Maintain Kinetochore-Microtubule Attachment throughout Mitosis and Rarely Break during Anaphase

Judit Pampalona,

Current address: Cell Division Group, Institute for Research in Biomedicine Barcelona, C/ Baldiri Reixac 10–12, Barcelona, E-08028, Spain

Affiliations Department of Biological Sciences, Virginia Tech, Blacksburg, VA 24061, United States of America, Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra, E-08193, Spain
⨯
Emanuele Roscioli,

Current address: Mechanochemical Cell Biology Building, Division of Biomedical Cell Biology, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, United Kingdom

Affiliations Department of Biological Sciences, Virginia Tech, Blacksburg, VA 24061, United States of America, Biocomplexity Institute of Virginia Tech, Blacksburg, VA 24061, United States of America
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William T. Silkworth,

Current address: Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, CA, 90095, United States of America

Affiliation Department of Biological Sciences, Virginia Tech, Blacksburg, VA 24061, United States of America
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Brent Bowden,

Current address: Department of Chemistry, Virginia Tech, Blacksburg, VA 24061, United States of America

Affiliation Department of Biological Sciences, Virginia Tech, Blacksburg, VA 24061, United States of America
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Anna Genescà,

Affiliation Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra, E-08193, Spain
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Laura Tusell,

Affiliation Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra, E-08193, Spain
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Daniela Cimini

* E-mail: cimini@vt.edu

Affiliation Department of Biological Sciences, Virginia Tech, Blacksburg, VA 24061, United States of America
⨯

Chromosome Bridges Maintain Kinetochore-Microtubule Attachment throughout Mitosis and Rarely Break during Anaphase

Judit Pampalona,
Emanuele Roscioli,
William T. Silkworth,
Brent Bowden,
Anna Genescà,
Laura Tusell,
Daniela Cimini

Published: January 19, 2016
https://doi.org/10.1371/journal.pone.0147420

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Microtubules
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Mitosis
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