AKT1E17K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer

Donatella Malanga; Stefania Belmonte; Fabiana Colelli; Marzia Scarfò; Carmela De Marco; Duarte Mendes Oliveira; Teresa Mirante; Caterina Camastra; Monica Gagliardi; Antonia Rizzuto; Chiara Mignogna; Orlando Paciello; Serenella Papparella; Henrik Fagman; Giuseppe Viglietto

doi:10.1371/journal.pone.0147334

Loading metrics

Open Access

Peer-reviewed

Research Article

AKT1^E17K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer

Donatella Malanga ,

* E-mail: viglietto@unicz.it (GV); malanga@unicz.it (DM)

Affiliations Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy, BIOGEM-Istituto di Ricerche Genetiche, Ariano Irpino (AV), Italy
⨯
Stefania Belmonte,

Affiliation BIOGEM-Istituto di Ricerche Genetiche, Ariano Irpino (AV), Italy
⨯
Fabiana Colelli,

Affiliation BIOGEM-Istituto di Ricerche Genetiche, Ariano Irpino (AV), Italy
⨯
Marzia Scarfò,

Affiliation BIOGEM-Istituto di Ricerche Genetiche, Ariano Irpino (AV), Italy
⨯
Carmela De Marco,

Affiliations Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy, BIOGEM-Istituto di Ricerche Genetiche, Ariano Irpino (AV), Italy
⨯
Duarte Mendes Oliveira,

Affiliation Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy
⨯
Teresa Mirante,

Affiliation Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy
⨯
Caterina Camastra,

Affiliation Dipartimento di Scienze della Salute, Unità di Anatomia Patologica, Università Magna Graecia, Catanzaro, Italy
⨯
Monica Gagliardi,

Affiliation IBFM-CNR, c/o Università Magna Graecia, Catanzaro, Italy
⨯
Antonia Rizzuto,

Affiliation Dipartimento di Scienze Mediche e Chirurgiche, Università Magna Graecia, Catanzaro, Italy
⨯
Chiara Mignogna,

Affiliation Dipartimento di Scienze della Salute, Unità di Anatomia Patologica, Università Magna Graecia, Catanzaro, Italy
⨯
Orlando Paciello,

Affiliation Department of Veterinary Medicine and Animal Productions, Università Federico II, Napoli, Italy
⨯
Serenella Papparella,

Affiliation Department of Veterinary Medicine and Animal Productions, Università Federico II, Napoli, Italy
⨯
Henrik Fagman,

Affiliation Department of Clinical Pathology and Genetics, Sahlgrenska University Hospital, Göteborg, Sweden
⨯
Giuseppe Viglietto

* E-mail: viglietto@unicz.it (GV); malanga@unicz.it (DM)

Affiliations Dipartimento di Medicina Sperimentale e Clinica, Università Magna Graecia, Catanzaro, Italy, BIOGEM-Istituto di Ricerche Genetiche, Ariano Irpino (AV), Italy
⨯

AKT1^E17K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer

Donatella Malanga,
Stefania Belmonte,
Fabiana Colelli,
Marzia Scarfò,
Carmela De Marco,
Duarte Mendes Oliveira,
Teresa Mirante,
Caterina Camastra,
Monica Gagliardi,
Antonia Rizzuto

Published: February 9, 2016
https://doi.org/10.1371/journal.pone.0147334

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Lung and intrathoracic tumors
Is the Subject Area "Lung and intrathoracic tumors" applicable to this article?

Thanks for your feedback.
Secondary lung tumors
Is the Subject Area "Secondary lung tumors" applicable to this article?

Thanks for your feedback.
Genetically modified animals
Is the Subject Area "Genetically modified animals" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Urethanes
Is the Subject Area "Urethanes" applicable to this article?

Thanks for your feedback.
Adenocarcinoma of the lung
Is the Subject Area "Adenocarcinoma of the lung" applicable to this article?

Thanks for your feedback.
Lung development
Is the Subject Area "Lung development" applicable to this article?

Thanks for your feedback.
Polymerase chain reaction
Is the Subject Area "Polymerase chain reaction" applicable to this article?

Thanks for your feedback.