A Low Mortality, High Morbidity Reduced Intensity Status Epilepticus (RISE) Model of Epilepsy and Epileptogenesis in the Rat

Tamara Modebadze; Nicola H. Morgan; Isabelle A. A. Pérès; Rebecca D. Hadid; Naoki Amada; Charlotte Hill; Claire Williams; Ian M. Stanford; Christopher M. Morris; Roland S. G. Jones; Benjamin J. Whalley; Gavin L. Woodhall

doi:10.1371/journal.pone.0147265

Loading metrics

Open Access

Peer-reviewed

Research Article

A Low Mortality, High Morbidity Reduced Intensity Status Epilepticus (RISE) Model of Epilepsy and Epileptogenesis in the Rat

Tamara Modebadze ,

Contributed equally to this work with: Tamara Modebadze, Nicola H. Morgan

Affiliation Aston Brain Centre, Aston University, School of Life and Health Sciences, Birmingham, United Kingdom
⨯
Nicola H. Morgan ,

Contributed equally to this work with: Tamara Modebadze, Nicola H. Morgan

Affiliation Aston Brain Centre, Aston University, School of Life and Health Sciences, Birmingham, United Kingdom
⨯
Isabelle A. A. Pérès,

Affiliation School of Pharmacy, Hopkins Life Sciences Building, University of Reading, Whiteknights, Reading, Berkshire, United Kingdom
⨯
Rebecca D. Hadid,

Affiliation School of Pharmacy, Hopkins Life Sciences Building, University of Reading, Whiteknights, Reading, Berkshire, United Kingdom
⨯
Naoki Amada,

Affiliation School of Pharmacy, Hopkins Life Sciences Building, University of Reading, Whiteknights, Reading, Berkshire, United Kingdom
⨯
Charlotte Hill,

Affiliation School of Pharmacy, Hopkins Life Sciences Building, University of Reading, Whiteknights, Reading, Berkshire, United Kingdom
⨯
Claire Williams,

Affiliation School of Pharmacy, Hopkins Life Sciences Building, University of Reading, Whiteknights, Reading, Berkshire, United Kingdom
⨯
Ian M. Stanford,

Affiliation Aston Brain Centre, Aston University, School of Life and Health Sciences, Birmingham, United Kingdom
⨯
Christopher M. Morris,

Affiliation Medical Toxicology Centre, Newcastle University, Wolfson Building, Claremont Place, Newcastle upon Tyne, United Kingdom
⨯
Roland S. G. Jones,

Affiliation Department of Pharmacology, University of Bath, Claverton Down, Bath, United Kingdom
⨯
Benjamin J. Whalley,

Affiliation School of Pharmacy, Hopkins Life Sciences Building, University of Reading, Whiteknights, Reading, Berkshire, United Kingdom
⨯
Gavin L. Woodhall

* E-mail: g.l.woodhall@aston.ac.uk

Affiliation Aston Brain Centre, Aston University, School of Life and Health Sciences, Birmingham, United Kingdom
⨯

A Low Mortality, High Morbidity Reduced Intensity Status Epilepticus (RISE) Model of Epilepsy and Epileptogenesis in the Rat

Tamara Modebadze,
Nicola H. Morgan,
Isabelle A. A. Pérès,
Rebecca D. Hadid,
Naoki Amada,
Charlotte Hill,
Claire Williams,
Ian M. Stanford,
Christopher M. Morris,
Roland S. G. Jones

Published: February 24, 2016
https://doi.org/10.1371/journal.pone.0147265

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Epilepsy
Is the Subject Area "Epilepsy" applicable to this article?

Thanks for your feedback.
Death rates
Is the Subject Area "Death rates" applicable to this article?

Thanks for your feedback.
Brain damage
Is the Subject Area "Brain damage" applicable to this article?

Thanks for your feedback.
Hippocampus
Is the Subject Area "Hippocampus" applicable to this article?

Thanks for your feedback.
Animal behavior
Is the Subject Area "Animal behavior" applicable to this article?

Thanks for your feedback.
Rats
Is the Subject Area "Rats" applicable to this article?

Thanks for your feedback.
Neural networks
Is the Subject Area "Neural networks" applicable to this article?

Thanks for your feedback.
Status epilepticus
Is the Subject Area "Status epilepticus" applicable to this article?

Thanks for your feedback.