Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin-CreERT2/Diphtheria Toxin Fragment A Transgenic Mice

Sanghee Yun; Michael H. Donovan; Michele N. Ross; Devon R. Richardson; Robin Reister; Laure A. Farnbauch; Stephanie J. Fischer; Dieter Riethmacher; Howard K. Gershenfeld; Diane C. Lagace; Amelia J. Eisch

doi:10.1371/journal.pone.0147256

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Research Article

Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin-CreER^T2/Diphtheria Toxin Fragment A Transgenic Mice

Sanghee Yun,

Affiliation Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX, United States of America
⨯
Michael H. Donovan,

Affiliation Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX, United States of America
⨯
Michele N. Ross,

Affiliation Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX, United States of America
⨯
Devon R. Richardson,

Affiliation Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX, United States of America
⨯
Robin Reister,

Affiliation Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX, United States of America
⨯
Laure A. Farnbauch,

Affiliation Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX, United States of America
⨯
Stephanie J. Fischer,

Affiliation Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX, United States of America
⨯
Dieter Riethmacher,

Affiliations Department of Biomedical Sciences, Nazarbayev University School of Medicine, Astana, Kazakhstan, Human Development and Health, School of Medicine, Southampton General Hospital, Southampton University, Southampton, United Kingdom
⨯
Howard K. Gershenfeld,

Affiliation Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX, United States of America
⨯
Diane C. Lagace ,

* E-mail: amelia.eisch@utsouthwestern.edu (AJE); diane.lagace@uottawa.ca (DCL)

¶‡ These authors are joint senior authors on this work.

Affiliation Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX, United States of America
⨯
Amelia J. Eisch

* E-mail: amelia.eisch@utsouthwestern.edu (AJE); diane.lagace@uottawa.ca (DCL)

¶‡ These authors are joint senior authors on this work.

Affiliation Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX, United States of America
⨯

Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin-CreER^T2/Diphtheria Toxin Fragment A Transgenic Mice

Sanghee Yun,
Michael H. Donovan,
Michele N. Ross,
Devon R. Richardson,
Robin Reister,
Laure A. Farnbauch,
Stephanie J. Fischer,
Dieter Riethmacher,
Howard K. Gershenfeld,
Diane C. Lagace

Published: January 21, 2016
https://doi.org/10.1371/journal.pone.0147256

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