Cigarette Smoke Disturbs the Survival of CD8+ Tc/Tregs Partially through Muscarinic Receptors-Dependent Mechanisms in Chronic Obstructive Pulmonary Disease

Gang Chen; Mei Zhou; Long Chen; Zhao-Ji Meng; Xian-Zhi Xiong; Hong-Ju Liu; Jian-Bao Xin; Jian-Chu Zhang

doi:10.1371/journal.pone.0147232

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Open Access

Peer-reviewed

Research Article

Cigarette Smoke Disturbs the Survival of CD8⁺ Tc/Tregs Partially through Muscarinic Receptors-Dependent Mechanisms in Chronic Obstructive Pulmonary Disease

Gang Chen ,

Contributed equally to this work with: Gang Chen, Mei Zhou

Affiliation Department of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Mei Zhou ,

Contributed equally to this work with: Gang Chen, Mei Zhou

Affiliation Department of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Long Chen,

Affiliation Department of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Zhao-Ji Meng,

Affiliation Department of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Xian-Zhi Xiong ,

* E-mail: xxz0508@hust.edu.cn

Affiliation Department of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Hong-Ju Liu,

Affiliation Department of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Jian-Bao Xin,

Affiliation Department of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Jian-Chu Zhang

Affiliation Department of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯

Cigarette Smoke Disturbs the Survival of CD8⁺ Tc/Tregs Partially through Muscarinic Receptors-Dependent Mechanisms in Chronic Obstructive Pulmonary Disease

Gang Chen,
Mei Zhou,
Long Chen,
Zhao-Ji Meng,
Xian-Zhi Xiong,
Hong-Ju Liu,
Jian-Bao Xin,
Jian-Chu Zhang

Published: January 25, 2016
https://doi.org/10.1371/journal.pone.0147232

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