Overexpression of Heme Oxygenase-1 Prevents Renal Interstitial Inflammation and Fibrosis Induced by Unilateral Ureter Obstruction

Xiao Chen; Shi-Yao Wei; Jian-Si Li; Qing-Fang Zhang; Yu-Xiao Wang; Shi-Lei Zhao; Jing Yu; Chang Wang; Ying Qin; Qiu-Ju Wei; Gui-Xiang Lv; Bing Li

doi:10.1371/journal.pone.0147084

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Open Access

Peer-reviewed

Research Article

Overexpression of Heme Oxygenase-1 Prevents Renal Interstitial Inflammation and Fibrosis Induced by Unilateral Ureter Obstruction

Xiao Chen ,

Contributed equally to this work with: Xiao Chen, Shi-Yao Wei

Affiliation Department of Nephrology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Shi-Yao Wei ,

Contributed equally to this work with: Xiao Chen, Shi-Yao Wei

Affiliation Department of Nephrology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Jian-Si Li,

Affiliation Department of Nephrology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Qing-Fang Zhang,

Affiliation Department of Nephrology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Yu-Xiao Wang,

Affiliation Department of Nephrology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Shi-Lei Zhao,

Affiliation Department of Nephrology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Jing Yu,

Affiliation Department of Nephrology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Chang Wang,

Affiliation Department of Nephrology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Ying Qin,

Affiliation Department of Nephrology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Qiu-Ju Wei,

Affiliation Department of Nephrology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Gui-Xiang Lv ,

* E-mail: icecreamlee@hotmail.com (BL); lvguixianghyd@163.com (G-XL)

Affiliation Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China
⨯
Bing Li

* E-mail: icecreamlee@hotmail.com (BL); lvguixianghyd@163.com (G-XL)

Affiliation Department of Nephrology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, China
⨯

Overexpression of Heme Oxygenase-1 Prevents Renal Interstitial Inflammation and Fibrosis Induced by Unilateral Ureter Obstruction

Xiao Chen,
Shi-Yao Wei,
Jian-Si Li,
Qing-Fang Zhang,
Yu-Xiao Wang,
Shi-Lei Zhao,
Jing Yu,
Chang Wang,
Ying Qin,
Qiu-Ju Wei

Published: January 14, 2016
https://doi.org/10.1371/journal.pone.0147084

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