Lung Infection by Human Bocavirus Induces the Release of Profibrotic Mediator Cytokines In Vivo and In Vitro

Soumaya Khalfaoui; Vivien Eichhorn; Christian Karagiannidis; Inga Bayh; Michael Brockmann; Monika Pieper; Wolfram Windisch; Oliver Schildgen; Verena Schildgen

doi:10.1371/journal.pone.0147010

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Peer-reviewed

Research Article

Lung Infection by Human Bocavirus Induces the Release of Profibrotic Mediator Cytokines In Vivo and In Vitro

Soumaya Khalfaoui ,

Contributed equally to this work with: Soumaya Khalfaoui, Vivien Eichhorn

Affiliation Kliniken der Stadt Köln gGmbH, University Hospital Witten/Herdecke, Cologne-Merheim, Ostmerheimer Strasse 200, Institute for Pathology, D-51109 Cologne, Germany
⨯
Vivien Eichhorn ,

Contributed equally to this work with: Soumaya Khalfaoui, Vivien Eichhorn

Affiliation Kliniken der Stadt Köln gGmbH, University Hospital Witten/Herdecke, Cologne-Merheim, Ostmerheimer Strasse 200, Institute for Pathology, D-51109 Cologne, Germany
⨯
Christian Karagiannidis,

Affiliation Kliniken der Stadt Köln gGmbH, University Hospital Witten/Herdecke, Cologne-Merheim, Ostmerheimer Strasse 200, Department of Pneumology and Critical Care Medicine, D-51109 Cologne, Germany
⨯
Inga Bayh,

Affiliation Institute for Medical Biometry and Epidemiology, Faculty of Health, Alfred-Herrhausen-Str. 50, Witten/Herdecke University, Witten, Germany
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Michael Brockmann,

Affiliation Kliniken der Stadt Köln gGmbH, University Hospital Witten/Herdecke, Cologne-Merheim, Ostmerheimer Strasse 200, Institute for Pathology, D-51109 Cologne, Germany
⨯
Monika Pieper,

Affiliation Kliniken der Stadt Köln gGmbH, University Hospital Witten/Herdecke, Cologne-Merheim, Ostmerheimer Strasse 200, Institute for Pathology, D-51109 Cologne, Germany
⨯
Wolfram Windisch,

Affiliation Kliniken der Stadt Köln gGmbH, University Hospital Witten/Herdecke, Cologne-Merheim, Ostmerheimer Strasse 200, Department of Pneumology and Critical Care Medicine, D-51109 Cologne, Germany
⨯
Oliver Schildgen,

Affiliation Kliniken der Stadt Köln gGmbH, University Hospital Witten/Herdecke, Cologne-Merheim, Ostmerheimer Strasse 200, Institute for Pathology, D-51109 Cologne, Germany
⨯
Verena Schildgen

* E-mail: schildgenv@kliniken-koeln.de; verena.schildgen@uni-wh.de

Affiliation Kliniken der Stadt Köln gGmbH, University Hospital Witten/Herdecke, Cologne-Merheim, Ostmerheimer Strasse 200, Institute for Pathology, D-51109 Cologne, Germany
⨯

Lung Infection by Human Bocavirus Induces the Release of Profibrotic Mediator Cytokines In Vivo and In Vitro

Soumaya Khalfaoui,
Vivien Eichhorn,
Christian Karagiannidis,
Inga Bayh,
Michael Brockmann,
Monika Pieper,
Wolfram Windisch,
Oliver Schildgen,
Verena Schildgen

Published: January 25, 2016
https://doi.org/10.1371/journal.pone.0147010

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Respiratory infections
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Fibrosis
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Lung and intrathoracic tumors
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Human bocavirus infection
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