A Method to Quantify Cell-Free Fetal DNA Fraction in Maternal Plasma Using Next Generation Sequencing: Its Application in Non-Invasive Prenatal Chromosomal Aneuploidy Detection

Open Access

Peer-reviewed

Research Article

Xu-Ping Xu,

Affiliation Institute of Antibody Engineering, School of Biotechnology, Southern Medical University, Guangzhou, China
⨯
Hai-Yan Gan,

Affiliation Guangzhou Darui Biotechnology Co. LTD, Guangzhou, China
⨯
Fen-Xia Li,

Affiliation Guangzhou Darui Biotechnology Co. LTD, Guangzhou, China
⨯
Qi Tian,

Affiliation The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
⨯
Jun Zhang,

Affiliation The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
⨯
Rong-Liang Liang,

Affiliation Institute of Antibody Engineering, School of Biotechnology, Southern Medical University, Guangzhou, China
⨯
Ming Li,

Affiliation Institute of Antibody Engineering, School of Biotechnology, Southern Medical University, Guangzhou, China
⨯
Xue-Xi Yang ,

Contributed equally to this work with: Xue-Xi Yang, Ying-Song Wu

* E-mail: wg@smu.edu.cn (YSW); yxxzb@sohu.com (XXY)

Affiliation Institute of Antibody Engineering, School of Biotechnology, Southern Medical University, Guangzhou, China
⨯
Ying-Song Wu

Contributed equally to this work with: Xue-Xi Yang, Ying-Song Wu

* E-mail: wg@smu.edu.cn (YSW); yxxzb@sohu.com (XXY)

Affiliation Institute of Antibody Engineering, School of Biotechnology, Southern Medical University, Guangzhou, China
⨯

Reader Comments (0)

DNA library construction
Is the Subject Area "DNA library construction" applicable to this article?

Thanks for your feedback.
Pregnancy
Is the Subject Area "Pregnancy" applicable to this article?

Thanks for your feedback.
Aneuploidy
Is the Subject Area "Aneuploidy" applicable to this article?

Thanks for your feedback.
DNA sequencing
Is the Subject Area "DNA sequencing" applicable to this article?

Thanks for your feedback.
Down syndrome
Is the Subject Area "Down syndrome" applicable to this article?

Thanks for your feedback.
Y chromosomes
Is the Subject Area "Y chromosomes" applicable to this article?

Thanks for your feedback.
Blood plasma
Is the Subject Area "Blood plasma" applicable to this article?

Thanks for your feedback.
Next-generation sequencing
Is the Subject Area "Next-generation sequencing" applicable to this article?

Thanks for your feedback.