Genetic Determinants of Thrombin Generation and Their Relation to Venous Thrombosis: Results from the GAIT-2 Project

Laura Martin-Fernandez; Andrey Ziyatdinov; Marina Carrasco; Juan Antonio Millon; Angel Martinez-Perez; Noelia Vilalta; Helena Brunel; Montserrat Font; Anders Hamsten; Juan Carlos Souto; José Manuel Soria

doi:10.1371/journal.pone.0146922

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Open Access

Peer-reviewed

Research Article

Genetic Determinants of Thrombin Generation and Their Relation to Venous Thrombosis: Results from the GAIT-2 Project

Laura Martin-Fernandez,

Affiliation Unit of Genomics of Complex Diseases, Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain
⨯
Andrey Ziyatdinov,

Affiliation Unit of Genomics of Complex Diseases, Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain
⨯
Marina Carrasco,

Affiliation Unit of Hemostasis and Thrombosis, Department of Hematology, IIB-Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
⨯
Juan Antonio Millon,

Affiliation Unit of Hemostasis and Thrombosis, Department of Hematology, IIB-Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
⨯
Angel Martinez-Perez,

Affiliation Unit of Genomics of Complex Diseases, Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain
⨯
Noelia Vilalta,

Affiliation Unit of Hemostasis and Thrombosis, Department of Hematology, IIB-Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
⨯
Helena Brunel,

Affiliation Unit of Genomics of Complex Diseases, Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain
⨯
Montserrat Font,

Affiliation Unit of Hemostasis and Thrombosis, Department of Hematology, IIB-Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
⨯
Anders Hamsten,

Affiliation Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
⨯
Juan Carlos Souto ,

* E-mail: jsouto@santpau.cat

Affiliation Unit of Hemostasis and Thrombosis, Department of Hematology, IIB-Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
⨯
José Manuel Soria

Affiliation Unit of Genomics of Complex Diseases, Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain
⨯

Genetic Determinants of Thrombin Generation and Their Relation to Venous Thrombosis: Results from the GAIT-2 Project

Laura Martin-Fernandez,
Andrey Ziyatdinov,
Marina Carrasco,
Juan Antonio Millon,
Angel Martinez-Perez,
Noelia Vilalta,
Helena Brunel,
Montserrat Font,
Anders Hamsten,
Juan Carlos Souto

Published: January 19, 2016
https://doi.org/10.1371/journal.pone.0146922

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Venous thromboembolism
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