Benefits and Challenges with Applying Unique Molecular Identifiers in Next Generation Sequencing to Detect Low Frequency Mutations

Open Access

Peer-reviewed

Research Article

Ruqin Kou,

Affiliation Department of Development, GENEWIZ LLC, 115 Corporate Blvd., South Plainfield, NJ, 07080, United States of America
⨯
Ham Lam,

Affiliation Department of Development, GENEWIZ LLC, 115 Corporate Blvd., South Plainfield, NJ, 07080, United States of America
⨯
Hairong Duan,

Affiliation Department of Bioinformatics, GENEWIZ CN, 218 Xinghu Street, Suzhou, Jiangsu, 215123, China
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Li Ye,

Affiliation Department of Bioinformatics, GENEWIZ CN, 218 Xinghu Street, Suzhou, Jiangsu, 215123, China
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Narisra Jongkam,

Affiliation Department of Development, GENEWIZ LLC, 115 Corporate Blvd., South Plainfield, NJ, 07080, United States of America
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Weizhi Chen,

Affiliation Department of Bioinformatics, GENEWIZ CN, 218 Xinghu Street, Suzhou, Jiangsu, 215123, China
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Shifang Zhang,

Affiliation Department of Development, GENEWIZ LLC, 115 Corporate Blvd., South Plainfield, NJ, 07080, United States of America
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Shihong Li

* E-mail: shihong.li@genewiz.com

Affiliation Department of Development, GENEWIZ LLC, 115 Corporate Blvd., South Plainfield, NJ, 07080, United States of America
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Polymerase chain reaction
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Nucleotide sequencing
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Nucleotides
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Mutation detection
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Platinum
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DNA polymerase
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DNA sequencing
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Human genomics
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