Comparative MD Simulations Indicate a Dual Role for Arg1323.50 in Dopamine-Dependent D2R Activation

Open Access

Peer-reviewed

Research Article

Comparative MD Simulations Indicate a Dual Role for Arg132^3.50 in Dopamine-Dependent D2R Activation

Ralf C. Kling,

Affiliations Department of Chemistry and Pharmacy, Emil Fischer Center, Friedrich Alexander University, Erlangen, Germany, Department of Chemistry and Pharmacy, Computer Chemistry Center, Friedrich Alexander University, Erlangen, Germany
⨯
Timothy Clark,

Affiliations Department of Chemistry and Pharmacy, Computer Chemistry Center, Friedrich Alexander University, Erlangen, Germany, Centre for Molecular Design, University of Portsmouth, King Henry Building, Portsmouth, United Kingdom
⨯
Peter Gmeiner

* E-mail: peter.gmeiner@fau.de

Affiliation Department of Chemistry and Pharmacy, Emil Fischer Center, Friedrich Alexander University, Erlangen, Germany
⨯

Dopamine
Is the Subject Area "Dopamine" applicable to this article?

Thanks for your feedback.
Biochemical simulations
Is the Subject Area "Biochemical simulations" applicable to this article?

Thanks for your feedback.
Protein interactions
Is the Subject Area "Protein interactions" applicable to this article?

Thanks for your feedback.
G protein coupled receptors
Is the Subject Area "G protein coupled receptors" applicable to this article?

Thanks for your feedback.
Crystal structure
Is the Subject Area "Crystal structure" applicable to this article?

Thanks for your feedback.
Intracellular receptors
Is the Subject Area "Intracellular receptors" applicable to this article?

Thanks for your feedback.
Simulation and modeling
Is the Subject Area "Simulation and modeling" applicable to this article?

Thanks for your feedback.
Protein structure
Is the Subject Area "Protein structure" applicable to this article?

Thanks for your feedback.