The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice

Yasushi Honda; Kento Imajo; Takayuki Kato; Takaomi Kessoku; Yuji Ogawa; Wataru Tomeno; Shingo Kato; Hironori Mawatari; Koji Fujita; Masato Yoneda; Satoru Saito; Atsushi Nakajima

doi:10.1371/journal.pone.0146337

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Peer-reviewed

Research Article

The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice

Yasushi Honda,

Affiliation Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Kento Imajo,

Affiliation Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Takayuki Kato,

Affiliation Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Takaomi Kessoku,

Affiliation Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Yuji Ogawa,

Affiliation Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Wataru Tomeno,

Affiliation Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Shingo Kato,

Affiliation Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Hironori Mawatari,

Affiliation Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Koji Fujita,

Affiliation Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Masato Yoneda,

Affiliation Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Satoru Saito,

Affiliation Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Atsushi Nakajima

* E-mail: nakajima-tky@umin.ac.jp

Affiliation Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯

The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice

Yasushi Honda,
Kento Imajo,
Takayuki Kato,
Takaomi Kessoku,
Yuji Ogawa,
Wataru Tomeno,
Shingo Kato,
Hironori Mawatari,
Koji Fujita,
Masato Yoneda

Published: January 5, 2016
https://doi.org/10.1371/journal.pone.0146337

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