Expression and Polymorphism of Toll-Like Receptor 4 and Effect on NF-κB Mediated Inflammation in Colon Cancer Patients

Abdelhabib Semlali; Narasimha Reddy Parine; Maha Arafah; Lamjed Mansour; Arezki Azzi; Omair Al Shahrani; Abdullah Al Amri; Jilani P. Shaik; Abdulrahman M. Aljebreen; Othman Alharbi; Majid A. Almadi; Nahla Ali Azzam; Muhammad Kohailan; Mahmoud Rouabhia; Mohammad Saud Alanazi

doi:10.1371/journal.pone.0146333

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Open Access

Peer-reviewed

Research Article

Expression and Polymorphism of Toll-Like Receptor 4 and Effect on NF-κB Mediated Inflammation in Colon Cancer Patients

Abdelhabib Semlali ,

* E-mail: asemlali@ksu.edu.sa; semlali.abdelhabib@gmail.com

Affiliation Genome Research Chair, Department of Biochemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯
Narasimha Reddy Parine,

Affiliation Genome Research Chair, Department of Biochemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯
Maha Arafah,

Affiliation College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯
Lamjed Mansour,

Affiliation Department of Zoology, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯
Arezki Azzi,

Affiliation College of Medicine, Al Imam Muhammad Ibn Saud Islamic University (IMSIU), Riyadh, Kingdom of Saudi Arabia
⨯
Omair Al Shahrani,

Affiliation Genome Research Chair, Department of Biochemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯
Abdullah Al Amri,

Affiliation Genome Research Chair, Department of Biochemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯
Jilani P. Shaik,

Affiliation Genome Research Chair, Department of Biochemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯
Abdulrahman M. Aljebreen,

Affiliations College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, Division of Gastroenterology, King Khalid University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯
Othman Alharbi,

Affiliations College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, Division of Gastroenterology, King Khalid University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯
Majid A. Almadi,

Affiliations Division of Gastroenterology, King Khalid University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia, Division of Gastroenterology, The McGill University Health Center, Montreal General Hospital, McGill University, Montreal, Québec, Canada
⨯
Nahla Ali Azzam,

Affiliations College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, Division of Gastroenterology, King Khalid University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯
Muhammad Kohailan,

Affiliation Genome Research Chair, Department of Biochemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯
Mahmoud Rouabhia,

Affiliation Groupe de Recherche en Écologie Buccale, Département de stomatologie, Faculté de Médecine Dentaire, Université Laval, Québec, Québec, Canada
⨯
Mohammad Saud Alanazi

Affiliation Genome Research Chair, Department of Biochemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia
⨯

Expression and Polymorphism of Toll-Like Receptor 4 and Effect on NF-κB Mediated Inflammation in Colon Cancer Patients

Abdelhabib Semlali,
Narasimha Reddy Parine,
Maha Arafah,
Lamjed Mansour,
Arezki Azzi,
Omair Al Shahrani,
Abdullah Al Amri,
Jilani P. Shaik,
Abdulrahman M. Aljebreen,
Othman Alharbi

Published: January 15, 2016
https://doi.org/10.1371/journal.pone.0146333

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Single nucleotide polymorphisms
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Inflammation
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Toll-like receptors
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