In Vitro Comparison of the Activity Requirements and Substrate Specificity of Human and Triboleum castaneum PINK1 Orthologues

Open Access

Peer-reviewed

Research Article

Liesbeth Aerts,

Affiliations Center for the Biology of Disease, Flemish Institute for Biotechnology (VIB), Leuven, Belgium, Center for Human Genetics, Leuven Institute for Neurodegenerative Disorders and University Hospitals Leuven, University of Leuven, Leuven, Belgium
⨯
Katleen Craessaerts,

Affiliations Center for the Biology of Disease, Flemish Institute for Biotechnology (VIB), Leuven, Belgium, Center for Human Genetics, Leuven Institute for Neurodegenerative Disorders and University Hospitals Leuven, University of Leuven, Leuven, Belgium
⨯
Bart De Strooper ,

* E-mail: Bart.DeStrooper@cme.vib-kuleuven.be (BDS); vmorais@medicina.ulisboa.pt (VAM)

Affiliations Center for the Biology of Disease, Flemish Institute for Biotechnology (VIB), Leuven, Belgium, Center for Human Genetics, Leuven Institute for Neurodegenerative Disorders and University Hospitals Leuven, University of Leuven, Leuven, Belgium, Institute of Neurology, University College London, London, United Kingdom
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Vanessa A. Morais

* E-mail: Bart.DeStrooper@cme.vib-kuleuven.be (BDS); vmorais@medicina.ulisboa.pt (VAM)

Affiliations Center for the Biology of Disease, Flemish Institute for Biotechnology (VIB), Leuven, Belgium, Center for Human Genetics, Leuven Institute for Neurodegenerative Disorders and University Hospitals Leuven, University of Leuven, Leuven, Belgium, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
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Phosphorylation
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In vitro kinase assay
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Histones
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Mitochondria
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Parkinson disease
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Insects
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Polymerase chain reaction
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Radiolabeling
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