Chemical Composition and Biological Activity of Extracts Obtained by Supercritical Extraction and Ethanolic Extraction of Brown, Green and Red Propolis Derived from Different Geographic Regions in Brazil

• Bruna Aparecida Souza Machado ,

  * E-mail: brunamachado17@hotmail.com

  ¶‡ BASM and FFP contributed equally to this work. RPDS, GAB, DFS and JLCR also contributed equally to this work. SSC, HNB and MAUG also contributed equally to this work. OAD and JAPH also contributed equally to this work.

  Affiliations Institute of Research and Technology, Tiradentes University, Aracaju, Sergipe, Brazil, Faculty of Technology, SENAI/CIMATEC, National Service of Industrial Learning–SENAI, Salvador, Bahia, Brazil

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• Rejane Pina Dantas Silva ,

  ¶‡ BASM and FFP contributed equally to this work. RPDS, GAB, DFS and JLCR also contributed equally to this work. SSC, HNB and MAUG also contributed equally to this work. OAD and JAPH also contributed equally to this work.

  Affiliation Faculty of Technology, SENAI/CIMATEC, National Service of Industrial Learning–SENAI, Salvador, Bahia, Brazil

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• Gabriele de Abreu Barreto ,

  ¶‡ BASM and FFP contributed equally to this work. RPDS, GAB, DFS and JLCR also contributed equally to this work. SSC, HNB and MAUG also contributed equally to this work. OAD and JAPH also contributed equally to this work.

  Affiliation Faculty of Technology, SENAI/CIMATEC, National Service of Industrial Learning–SENAI, Salvador, Bahia, Brazil

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• Samantha Serra Costa ,

  ¶‡ BASM and FFP contributed equally to this work. RPDS, GAB, DFS and JLCR also contributed equally to this work. SSC, HNB and MAUG also contributed equally to this work. OAD and JAPH also contributed equally to this work.

  Affiliation Faculty of Technology, SENAI/CIMATEC, National Service of Industrial Learning–SENAI, Salvador, Bahia, Brazil

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• Danielle Figuerêdo da Silva ,

  ¶‡ BASM and FFP contributed equally to this work. RPDS, GAB, DFS and JLCR also contributed equally to this work. SSC, HNB and MAUG also contributed equally to this work. OAD and JAPH also contributed equally to this work.

  Affiliation Faculty of Pharmacy, State University of Feira de Santana, Feira de Santana, Bahia, Brazil

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• Hugo Neves Brandão ,

  ¶‡ BASM and FFP contributed equally to this work. RPDS, GAB, DFS and JLCR also contributed equally to this work. SSC, HNB and MAUG also contributed equally to this work. OAD and JAPH also contributed equally to this work.

  Affiliation Faculty of Pharmacy, State University of Feira de Santana, Feira de Santana, Bahia, Brazil

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• José Luiz Carneiro da Rocha ,

  ¶‡ BASM and FFP contributed equally to this work. RPDS, GAB, DFS and JLCR also contributed equally to this work. SSC, HNB and MAUG also contributed equally to this work. OAD and JAPH also contributed equally to this work.

  Affiliation Faculty of Pharmacy, State University of Feira de Santana, Feira de Santana, Bahia, Brazil

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• Odir Antônio Dellagostin ,

  ¶‡ BASM and FFP contributed equally to this work. RPDS, GAB, DFS and JLCR also contributed equally to this work. SSC, HNB and MAUG also contributed equally to this work. OAD and JAPH also contributed equally to this work.

  Affiliation Technology Development Center, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil

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• João Antônio Pegas Henriques ,

  ¶‡ BASM and FFP contributed equally to this work. RPDS, GAB, DFS and JLCR also contributed equally to this work. SSC, HNB and MAUG also contributed equally to this work. OAD and JAPH also contributed equally to this work.

  Affiliation Biotechnology, University of Caixias do Sul, Caixias do Sul, Rio Grande do Sul, Brazil

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• Marcelo Andres Umsza-Guez ,

  ¶‡ BASM and FFP contributed equally to this work. RPDS, GAB, DFS and JLCR also contributed equally to this work. SSC, HNB and MAUG also contributed equally to this work. OAD and JAPH also contributed equally to this work.

  Affiliation Biotechnology, Federal University of Bahia, Salvador, Bahia, Brazil

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• Francine Ferreira Padilha

  ¶‡ BASM and FFP contributed equally to this work. RPDS, GAB, DFS and JLCR also contributed equally to this work. SSC, HNB and MAUG also contributed equally to this work. OAD and JAPH also contributed equally to this work.

  Affiliation Institute of Research and Technology, Tiradentes University, Aracaju, Sergipe, Brazil

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