Aberrant Hypermethylation of SALL3 with HPV Involvement Contributes to the Carcinogenesis of Cervical Cancer

Xing Wei; Shaohua Zhang; Di Cao; Minyi Zhao; Qian Zhang; Juan Zhao; Ting Yang; Meili Pei; Li Wang; Yang Li; Xiaofeng Yang

doi:10.1371/journal.pone.0145700

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Peer-reviewed

Research Article

Aberrant Hypermethylation of SALL3 with HPV Involvement Contributes to the Carcinogenesis of Cervical Cancer

Xing Wei,

Affiliation Department of Gynecology and Obstetrics, The First Affiliated Hospital of Medical School, Xi’an Jiaotong University, 277 West Yanta Road, Xi’an 710061, China
⨯
Shaohua Zhang,

Affiliation Department of Gynecology and Obstetrics, The Affiliated Hospital of Xi’an Medical College, Xi’an 710077, China
⨯
Di Cao,

Affiliation Department of Gynecology and Obstetrics, The First Affiliated Hospital of Medical School, Xi’an Jiaotong University, 277 West Yanta Road, Xi’an 710061, China
⨯
Minyi Zhao,

Affiliation Department of Gynecology and Obstetrics, The First Affiliated Hospital of Medical School, Xi’an Jiaotong University, 277 West Yanta Road, Xi’an 710061, China
⨯
Qian Zhang,

Affiliation Department of Gynecology and Obstetrics, The First Affiliated Hospital of Medical School, Xi’an Jiaotong University, 277 West Yanta Road, Xi’an 710061, China
⨯
Juan Zhao,

Affiliation Department of Gynecology and Obstetrics, The First Affiliated Hospital of Medical School, Xi’an Jiaotong University, 277 West Yanta Road, Xi’an 710061, China
⨯
Ting Yang,

Affiliation Department of Gynecology and Obstetrics, The First Affiliated Hospital of Medical School, Xi’an Jiaotong University, 277 West Yanta Road, Xi’an 710061, China
⨯
Meili Pei,

Affiliation Department of Gynecology and Obstetrics, The First Affiliated Hospital of Medical School, Xi’an Jiaotong University, 277 West Yanta Road, Xi’an 710061, China
⨯
Li Wang,

Affiliation Center of Maternal and Child Health Care, The First Affiliated Hospital of Medical School, Xi’an Jiaotong University, 277 West Yanta Road, Xi’an 710061, China
⨯
Yang Li,

Affiliation Department of Gynecology and Obstetrics, The First Affiliated Hospital of Medical School, Xi’an Jiaotong University, 277 West Yanta Road, Xi’an 710061, China
⨯
Xiaofeng Yang

* E-mail: yxf73@163.com

Affiliation Department of Gynecology and Obstetrics, The First Affiliated Hospital of Medical School, Xi’an Jiaotong University, 277 West Yanta Road, Xi’an 710061, China
⨯

Aberrant Hypermethylation of SALL3 with HPV Involvement Contributes to the Carcinogenesis of Cervical Cancer

Xing Wei,
Shaohua Zhang,
Di Cao,
Minyi Zhao,
Qian Zhang,
Juan Zhao,
Ting Yang,
Meili Pei,
Li Wang,
Yang Li

Published: December 23, 2015
https://doi.org/10.1371/journal.pone.0145700

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Cervical cancer
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DNA methylation
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Promoter regions
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Methylation
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Human papillomavirus infection
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HeLa cells
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Cervix
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Gene expression
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