Inhibition of Hedgehog-Signaling Driven Genes in Prostate Cancer Cells by Sutherlandia frutescens Extract

Yuan Lu; Nicholas Starkey; Wei Lei; Jilong Li; Jianlin Cheng; William R. Folk; Dennis B. Lubahn

doi:10.1371/journal.pone.0145507

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Peer-reviewed

Research Article

Inhibition of Hedgehog-Signaling Driven Genes in Prostate Cancer Cells by Sutherlandia frutescens Extract

Yuan Lu,

Affiliations Department of Biochemistry, University of Missouri, Columbia, MO 65211, United States of America, MU Center for Botanical Interaction Studies, University of Missouri, Columbia, MO 65211, United States of America, Xiphophorus Genetic Stock Center, Texas State University, San Marcos, TX 78666, United States of America
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Nicholas Starkey,

Affiliations Department of Biochemistry, University of Missouri, Columbia, MO 65211, United States of America, MU Center for Botanical Interaction Studies, University of Missouri, Columbia, MO 65211, United States of America
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Wei Lei,

Affiliations MU Center for Botanical Interaction Studies, University of Missouri, Columbia, MO 65211, United States of America, Division of Animal Science, University of Missouri, Columbia, MO 65211, United States of America
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Jilong Li,

Affiliations MU Center for Botanical Interaction Studies, University of Missouri, Columbia, MO 65211, United States of America, Computer Science Department, University of Missouri, Columbia, MO 65211, United States of America, Informatics Institute, University of Missouri, Columbia, MO 65211, United States of America
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Jianlin Cheng,

Affiliations MU Center for Botanical Interaction Studies, University of Missouri, Columbia, MO 65211, United States of America, Computer Science Department, University of Missouri, Columbia, MO 65211, United States of America, Informatics Institute, University of Missouri, Columbia, MO 65211, United States of America
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William R. Folk,

Affiliations Department of Biochemistry, University of Missouri, Columbia, MO 65211, United States of America, MU Center for Botanical Interaction Studies, University of Missouri, Columbia, MO 65211, United States of America
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Dennis B. Lubahn

* E-mail: lubahnd@missouri.edu

Affiliations Department of Biochemistry, University of Missouri, Columbia, MO 65211, United States of America, MU Center for Botanical Interaction Studies, University of Missouri, Columbia, MO 65211, United States of America
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Inhibition of Hedgehog-Signaling Driven Genes in Prostate Cancer Cells by Sutherlandia frutescens Extract

Yuan Lu,
Nicholas Starkey,
Wei Lei,
Jilong Li,
Jianlin Cheng,
William R. Folk,
Dennis B. Lubahn

Published: December 28, 2015
https://doi.org/10.1371/journal.pone.0145507

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