Proanthocyanidins Extracted from Rhododendron pulchrum Leaves as Source of Tyrosinase Inhibitors: Structure, Activity, and Mechanism

Wei-Ming Chai; Rui Wang; Man-Kun Wei; Zheng-Rong Zou; Rong-Gen Deng; Wei-Sheng Liu; Yi-Yuan Peng

doi:10.1371/journal.pone.0145483

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Peer-reviewed

Research Article

Proanthocyanidins Extracted from Rhododendron pulchrum Leaves as Source of Tyrosinase Inhibitors: Structure, Activity, and Mechanism

Wei-Ming Chai ,

* E-mail: chaiweiming@jxnu.edu.cn (WMC); yiyuanpeng@jxnu.edu.cn (YYP)

Affiliations College of Life Science and Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University, Nanchang, Jiangxi 330022, People’s Republic of China, Key Laboratory of Poyang Lake Wetland and Watershed Research, Jiangxi Normal University, Nanchang, Jiangxi 330022, People’s Republic of China
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Rui Wang,

Affiliation College of Life Science and Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University, Nanchang, Jiangxi 330022, People’s Republic of China
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Man-Kun Wei,

Affiliation College of Life Science and Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University, Nanchang, Jiangxi 330022, People’s Republic of China
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Zheng-Rong Zou,

Affiliation College of Life Science and Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University, Nanchang, Jiangxi 330022, People’s Republic of China
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Rong-Gen Deng,

Affiliation College of Life Science and Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University, Nanchang, Jiangxi 330022, People’s Republic of China
⨯
Wei-Sheng Liu,

Affiliation College of Life Science and Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University, Nanchang, Jiangxi 330022, People’s Republic of China
⨯
Yi-Yuan Peng

* E-mail: chaiweiming@jxnu.edu.cn (WMC); yiyuanpeng@jxnu.edu.cn (YYP)

Affiliation College of Life Science and Key Laboratory of Small Functional Organic Molecule, Ministry of Education, Jiangxi Normal University, Nanchang, Jiangxi 330022, People’s Republic of China
⨯

Proanthocyanidins Extracted from Rhododendron pulchrum Leaves as Source of Tyrosinase Inhibitors: Structure, Activity, and Mechanism

Wei-Ming Chai,
Rui Wang,
Man-Kun Wei,
Zheng-Rong Zou,
Rong-Gen Deng,
Wei-Sheng Liu,
Yi-Yuan Peng

Published: December 29, 2015
https://doi.org/10.1371/journal.pone.0145483

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Matrix-assisted laser desorption ionization time-of-flight mass spectrometry
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Leaves
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Fluorescence
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Enzyme inhibitors
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