Comparative Proteomic Profiling of Ehrlichia ruminantium Pathogenic Strain and Its High-Passaged Attenuated Strain Reveals Virulence and Attenuation-Associated Proteins

• Isabel Marcelino ,

  * E-mail: Isabel.Marcelino@cirad.fr

  Affiliations Instituto de Biologia Experimental e Tecnológica (iBET), Oeiras, Portugal, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB-UNL), Oeiras, Portugal, CIRAD, UMR CMAEE, F-97170, Petit-Bourg, Guadeloupe, France, INRA, UMR1309 CMAEE, F-34398, Montpellier, France

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• Miguel Ventosa,

  Affiliations Instituto de Biologia Experimental e Tecnológica (iBET), Oeiras, Portugal, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB-UNL), Oeiras, Portugal

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• Elisabete Pires,

  Affiliation Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB-UNL), Oeiras, Portugal

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• Markus Müller,

  Affiliation Proteome Informatics, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland

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• Frédérique Lisacek,

  Affiliation Proteome Informatics, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland

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• Thierry Lefrançois,

  Affiliation CIRAD, UMR CMAEE, F-34398, Montpellier, France

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• Nathalie Vachiery,

  Affiliations CIRAD, UMR CMAEE, F-97170, Petit-Bourg, Guadeloupe, France, INRA, UMR1309 CMAEE, F-34398, Montpellier, France

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• Ana Varela Coelho

  Affiliation Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB-UNL), Oeiras, Portugal

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