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Open Access
Peer-reviewed
Research Article
Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis
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Alessandro Iannaccone ,
* E-mail: aiannacc@yahoo.com
Affiliation Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, United States of America
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Francesco Giorgianni,
Affiliation Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN, United States of America
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David D. New,
Affiliation Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, United States of America
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T. J. Hollingsworth,
Affiliation Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, United States of America
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Allison Umfress,
Current address: Vanderbilt University School of Medicine, Nashville, TN, United States of America
Affiliation Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, United States of America
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Albert H. Alhatem,
Affiliation Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, United States of America
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Indira Neeli,
Affiliations Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, United States of America, Department of Microbiology, Immunology & Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America
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Nataliya I. Lenchik,
Affiliations Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, United States of America, Department of Internal Medicine/Endocrinology, University of Tennessee Health Science Center, Memphis, TN, United States of America
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Barbara J. Jennings,
Affiliation Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, United States of America
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Jorge I. Calzada,
Affiliations Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, United States of America, Charles Retina Institute, Memphis, TN, United States of America
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Suzanne Satterfield,
Affiliation Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, United States of America
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Dennis Mathews,
Affiliations Eye Specialty Group, Memphis, TN, United States of America, Southern College of Optometry, Memphis, TN, United States of America
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Rocio I. Diaz,
Affiliations Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, United States of America, Charles Retina Institute, Memphis, TN, United States of America
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Tamara Harris,
Affiliation National Institute on Aging, NIH, Bethesda, MD, United States of America
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Karen C. Johnson,
Affiliation Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, United States of America
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Steve Charles,
Affiliations Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, United States of America, Charles Retina Institute, Memphis, TN, United States of America
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Stephen B. Kritchevsky,
Affiliations Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, United States of America, Sticht Center on Aging, Wake Forest University, Winston-Salem, NC, United States of America
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Ivan C. Gerling,
Affiliation Department of Internal Medicine/Endocrinology, University of Tennessee Health Science Center, Memphis, TN, United States of America
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Sarka Beranova-Giorgianni,
Affiliation Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN, United States of America
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Marko Z. Radic,
Affiliation Department of Microbiology, Immunology & Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America
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Health ABC study
¶Membership of the Health ABC study is provided in the Acknowledgments.
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Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis
- Alessandro Iannaccone,
- Francesco Giorgianni,
- David D. New,
- T. J. Hollingsworth,
- Allison Umfress,
- Albert H. Alhatem,
- Indira Neeli,
- Nataliya I. Lenchik,
- Barbara J. Jennings,
- Jorge I. Calzada
- Published: December 30, 2015
- https://doi.org/10.1371/journal.pone.0145323