ANKS1B Interacts with the Cerebral Cavernous Malformation Protein-1 and Controls Endothelial Permeability but Not Sprouting Angiogenesis

Stefanie E. Herberich; Ralph Klose; Iris Moll; Wan-Jen Yang; Joycelyn Wüstehube-Lausch; Andreas Fischer

doi:10.1371/journal.pone.0145304

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Open Access

Peer-reviewed

Research Article

ANKS1B Interacts with the Cerebral Cavernous Malformation Protein-1 and Controls Endothelial Permeability but Not Sprouting Angiogenesis

Stefanie E. Herberich ,

Contributed equally to this work with: Stefanie E. Herberich, Ralph Klose

Affiliations Vascular Signaling and Cancer (A270), German Cancer Research Center (DKFZ-ZMBH Alliance), D-69120, Heidelberg, Germany, Vascular Biology and Tumor Angiogenesis, Medical Faculty Mannheim (CBTM), Heidelberg University, D-68167, Mannheim, Germany
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Ralph Klose ,

Contributed equally to this work with: Stefanie E. Herberich, Ralph Klose

* E-mail: a.fischer@dkfz-heidelberg.de (AF); r.klose@dkfz-heidelberg.de (RK)

Affiliation Vascular Signaling and Cancer (A270), German Cancer Research Center (DKFZ-ZMBH Alliance), D-69120, Heidelberg, Germany
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Iris Moll,

Affiliation Vascular Signaling and Cancer (A270), German Cancer Research Center (DKFZ-ZMBH Alliance), D-69120, Heidelberg, Germany
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Wan-Jen Yang,

Affiliation Vascular Signaling and Cancer (A270), German Cancer Research Center (DKFZ-ZMBH Alliance), D-69120, Heidelberg, Germany
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Joycelyn Wüstehube-Lausch,

Current address: BioNTech AG, D-55131, Mainz, Germany

Affiliations Vascular Signaling and Cancer (A270), German Cancer Research Center (DKFZ-ZMBH Alliance), D-69120, Heidelberg, Germany, Vascular Biology and Tumor Angiogenesis, Medical Faculty Mannheim (CBTM), Heidelberg University, D-68167, Mannheim, Germany
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Andreas Fischer

* E-mail: a.fischer@dkfz-heidelberg.de (AF); r.klose@dkfz-heidelberg.de (RK)

Affiliations Vascular Signaling and Cancer (A270), German Cancer Research Center (DKFZ-ZMBH Alliance), D-69120, Heidelberg, Germany, Vascular Biology and Tumor Angiogenesis, Medical Faculty Mannheim (CBTM), Heidelberg University, D-68167, Mannheim, Germany, Department of Medicine I and Clinical Chemistry, Heidelberg University Hospital, D-69120, Heidelberg, Germany
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ANKS1B Interacts with the Cerebral Cavernous Malformation Protein-1 and Controls Endothelial Permeability but Not Sprouting Angiogenesis

Stefanie E. Herberich,
Ralph Klose,
Iris Moll,
Wan-Jen Yang,
Joycelyn Wüstehube-Lausch,
Andreas Fischer

Published: December 23, 2015
https://doi.org/10.1371/journal.pone.0145304

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Endothelial cells
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Small interfering RNA
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Transfection
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Protein interactions
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Permeability
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Electrical resistance
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