Confounding Factors in the Transcriptome Analysis of an In-Vivo Exposure Experiment

Oskar Bruning; Wendy Rodenburg; Paul F. K. Wackers; Conny van Oostrom; Martijs J. Jonker; Rob J. Dekker; Han Rauwerda; Wim A. Ensink; Annemieke de Vries; Timo M. Breit

doi:10.1371/journal.pone.0145252

Loading metrics

Open Access

Peer-reviewed

Research Article

Confounding Factors in the Transcriptome Analysis of an In-Vivo Exposure Experiment

Oskar Bruning ,

Contributed equally to this work with: Oskar Bruning, Wendy Rodenburg

Affiliation RNA Biology & Applied Bioinformatics research group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands
⨯
Wendy Rodenburg ,

Contributed equally to this work with: Oskar Bruning, Wendy Rodenburg

Affiliation Centre for Health Protection (GZB), National Institute of Public Health and the Environment (RIVM), Bilthoven, the Netherlands
⨯
Paul F. K. Wackers,

Affiliation RNA Biology & Applied Bioinformatics research group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands
⨯
Conny van Oostrom,

Affiliation Centre for Health Protection (GZB), National Institute of Public Health and the Environment (RIVM), Bilthoven, the Netherlands
⨯
Martijs J. Jonker,

Affiliation RNA Biology & Applied Bioinformatics research group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands
⨯
Rob J. Dekker,

Affiliation RNA Biology & Applied Bioinformatics research group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands
⨯
Han Rauwerda,

Affiliation RNA Biology & Applied Bioinformatics research group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands
⨯
Wim A. Ensink,

Affiliation RNA Biology & Applied Bioinformatics research group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands
⨯
Annemieke de Vries,

Affiliation Centre for Health Protection (GZB), National Institute of Public Health and the Environment (RIVM), Bilthoven, the Netherlands
⨯
Timo M. Breit

* E-mail: t.m.breit@uva.nl

Affiliation RNA Biology & Applied Bioinformatics research group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, the Netherlands
⨯

Confounding Factors in the Transcriptome Analysis of an In-Vivo Exposure Experiment

Oskar Bruning,
Wendy Rodenburg,
Paul F. K. Wackers,
Conny van Oostrom,
Martijs J. Jonker,
Rob J. Dekker,
Han Rauwerda,
Wim A. Ensink,
Annemieke de Vries,
Timo M. Breit

Published: January 20, 2016
https://doi.org/10.1371/journal.pone.0145252

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Transcriptome analysis
Is the Subject Area "Transcriptome analysis" applicable to this article?

Thanks for your feedback.
Biopsy
Is the Subject Area "Biopsy" applicable to this article?

Thanks for your feedback.
Analysis of variance
Is the Subject Area "Analysis of variance" applicable to this article?

Thanks for your feedback.
Microarrays
Is the Subject Area "Microarrays" applicable to this article?

Thanks for your feedback.
Circadian rhythms
Is the Subject Area "Circadian rhythms" applicable to this article?

Thanks for your feedback.
Experimental design
Is the Subject Area "Experimental design" applicable to this article?

Thanks for your feedback.
Principal component analysis
Is the Subject Area "Principal component analysis" applicable to this article?

Thanks for your feedback.