γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secretase Cleavage but Not Position of ε-Cleavage of the Amyloid Precursor Protein (APP)

• Christian B. Lessard,

  Affiliation Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Barbara A. Cottrell,

  Affiliation Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Hiroko Maruyama,

  Affiliation Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Suraj Suresh,

  Affiliation Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Todd E. Golde,

  Affiliation Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience, College of Medicine, University of Florida, Florida, United States of America

  ⨯
• Edward H. Koo

  * E-mail: edkoo@ucsd.edu

  Affiliations Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America, Departments of Medicine and Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

  ⨯