Anaplastic Lymphoma Kinase Rearrangement in Digestive Tract Cancer: Implication for Targeted Therapy in Chinese Population

Jianming Ying; Chen Lin; Jian Wu; Lei Guo; Tian Qiu; Yun Ling; Ling Shan; Haitao Zhou; Dongbing Zhao; Jian Wang; Jianwei Liang; Jianjun Zhao; Yuchen Jiao; Ning Lu; Hong Zhao

doi:10.1371/journal.pone.0144731

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Open Access

Peer-reviewed

Research Article

Anaplastic Lymphoma Kinase Rearrangement in Digestive Tract Cancer: Implication for Targeted Therapy in Chinese Population

Jianming Ying ,

Contributed equally to this work with: Jianming Ying, Chen Lin

Affiliation Department of Pathology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, PR China
⨯
Chen Lin ,

Contributed equally to this work with: Jianming Ying, Chen Lin

Affiliation Department of Abdominal Surgical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, PR China
⨯
Jian Wu,

Affiliation MyGenostics Inc., Baltimore, MD, United States of America
⨯
Lei Guo,

Affiliation Department of Pathology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, PR China
⨯
Tian Qiu,

Affiliation Department of Pathology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, PR China
⨯
Yun Ling,

Affiliation Department of Pathology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, PR China
⨯
Ling Shan,

Affiliation Department of Pathology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, PR China
⨯
Haitao Zhou,

Affiliation Department of Abdominal Surgical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, PR China
⨯
Dongbing Zhao,

Affiliation Department of Abdominal Surgical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, PR China
⨯
Jian Wang,

Affiliation Department of Abdominal Surgical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, PR China
⨯
Jianwei Liang,

Affiliation Department of Abdominal Surgical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, PR China
⨯
Jianjun Zhao,

Affiliation Department of Abdominal Surgical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, PR China
⨯
Yuchen Jiao ,

* E-mail: zhaohong9@sina.com (HZ); nlu03@126.com (NL); jiaoyuchen@cicams.ac.cn (YCJ)

Affiliation Laboratory of Cell and Molecular Biology & State Key Laboratory of Molecular Oncology, Cancer Institute & Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China
⨯
Ning Lu ,

* E-mail: zhaohong9@sina.com (HZ); nlu03@126.com (NL); jiaoyuchen@cicams.ac.cn (YCJ)

Affiliation Department of Pathology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, PR China
⨯
Hong Zhao

* E-mail: zhaohong9@sina.com (HZ); nlu03@126.com (NL); jiaoyuchen@cicams.ac.cn (YCJ)

Affiliation Department of Abdominal Surgical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, PR China
⨯

Anaplastic Lymphoma Kinase Rearrangement in Digestive Tract Cancer: Implication for Targeted Therapy in Chinese Population

Jianming Ying,
Chen Lin,
Jian Wu,
Lei Guo,
Tian Qiu,
Yun Ling,
Ling Shan,
Haitao Zhou,
Dongbing Zhao,
Jian Wang

Published: December 17, 2015
https://doi.org/10.1371/journal.pone.0144731

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