Identification of the Novel TMEM16A Inhibitor Dehydroandrographolide and Its Anticancer Activity on SW620 Cells

Yujie Sui; Fei Wu; Junfeng Lv; Hongxia Li; Xin Li; Zhenwu Du; Meiyan Sun; Yuhao Zheng; Longfei Yang; Lili Zhong; Xingyi Zhang; Guizhen Zhang

doi:10.1371/journal.pone.0144715

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Open Access

Peer-reviewed

Research Article

Identification of the Novel TMEM16A Inhibitor Dehydroandrographolide and Its Anticancer Activity on SW620 Cells

Yujie Sui,

Affiliation Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China
⨯
Fei Wu,

Affiliation Department of Gynecology and Obstetrics, Jilin University Bethune Second Hospital, Changchun, P. R. China
⨯
Junfeng Lv,

Affiliation Department of Radiology, Jilin University Bethune Second Hospital, Changchun, P. R. China
⨯
Hongxia Li,

Affiliation Department of Dermatology, Jilin University Bethune First Hospital, Changchun, P. R. China
⨯
Xin Li,

Affiliation Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China
⨯
Zhenwu Du,

Affiliation Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China
⨯
Meiyan Sun,

Affiliation Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China
⨯
Yuhao Zheng,

Affiliation Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China
⨯
Longfei Yang,

Affiliation Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China
⨯
Lili Zhong,

Affiliation Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China
⨯
Xingyi Zhang ,

* E-mail: xingyizhang@live.com (XYZ), Zhang4083@163.com (GZZ)

Affiliation Department of Thoracic Surgery, Jilin University Bethune Second Hospital, Changchun, P. R. China
⨯
Guizhen Zhang

* E-mail: xingyizhang@live.com (XYZ), Zhang4083@163.com (GZZ)

Affiliation Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China
⨯

Identification of the Novel TMEM16A Inhibitor Dehydroandrographolide and Its Anticancer Activity on SW620 Cells

Yujie Sui,
Fei Wu,
Junfeng Lv,
Hongxia Li,
Xin Li,
Zhenwu Du,
Meiyan Sun,
Yuhao Zheng,
Longfei Yang,
Lili Zhong

Published: December 11, 2015
https://doi.org/10.1371/journal.pone.0144715

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