Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1

Open Access

Peer-reviewed

Research Article

Claudia Breit,

Affiliation Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany
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Tanja Bange,

Affiliation Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany
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Arsen Petrovic,

Affiliation Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany
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John R. Weir,

Affiliation Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany
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Franziska Müller,

Affiliation Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany
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Doro Vogt,

Affiliation Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany
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Andrea Musacchio

* E-mail: andrea.musacchio@mpi-dortmund.mpg.de

Affiliations Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany, Centre for Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitätsstrasse, 45141, Essen, Germany
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Phosphorylation
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Nucleosomes
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Crystal structure
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Nucleotides
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Magnesium chloride
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In vitro kinase assay
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Phosphates
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Size-exclusion chromatography
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