Oral Administration of 4-Hydroxy-3-Methoxycinnamaldehyde Attenuates Atopic Dermatitis by Inhibiting T Cell and Keratinocyte Activation

Hyun-Su Lee; Eun-Ju Choi; Heeri Choi; Kyung-Sik Lee; Hye-Ran Kim; Bo-Ra Na; Min-Sung Kwon; Gil-Saeng Jeong; Hyun Gyu Choi; Eun Young Choi; Chang-Duk Jun

doi:10.1371/journal.pone.0144521

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Open Access

Peer-reviewed

Research Article

Oral Administration of 4-Hydroxy-3-Methoxycinnamaldehyde Attenuates Atopic Dermatitis by Inhibiting T Cell and Keratinocyte Activation

Hyun-Su Lee,

Affiliation School of Life Sciences, Immune Synapse Research Center and Cell Dynamics Research Center, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea
⨯
Eun-Ju Choi,

Affiliation Division of Sport Science, College of Natural Sciences, Konkuk University, Chungju, Republic of Korea
⨯
Heeri Choi,

Affiliation Division of Sport Science, College of Natural Sciences, Konkuk University, Chungju, Republic of Korea
⨯
Kyung-Sik Lee,

Affiliation School of Life Sciences, Immune Synapse Research Center and Cell Dynamics Research Center, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea
⨯
Hye-Ran Kim,

Affiliation School of Life Sciences, Immune Synapse Research Center and Cell Dynamics Research Center, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea
⨯
Bo-Ra Na,

Affiliation School of Life Sciences, Immune Synapse Research Center and Cell Dynamics Research Center, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea
⨯
Min-Sung Kwon,

Affiliation School of Life Sciences, Immune Synapse Research Center and Cell Dynamics Research Center, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea
⨯
Gil-Saeng Jeong,

Affiliation College of Pharmacy, Keimyung University, Daegu, Republic of Korea
⨯
Hyun Gyu Choi,

Affiliation College of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea
⨯
Eun Young Choi ,

* E-mail: choieun@ulsan.ac.kr (EYC); cdjun@gist.ac.kr (CDJ)

Affiliation Department of Biomedical Sciences, University of Ulsan College of Medicine, Seoul, Republic of Korea
⨯
Chang-Duk Jun

* E-mail: choieun@ulsan.ac.kr (EYC); cdjun@gist.ac.kr (CDJ)

Affiliation School of Life Sciences, Immune Synapse Research Center and Cell Dynamics Research Center, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea
⨯

Oral Administration of 4-Hydroxy-3-Methoxycinnamaldehyde Attenuates Atopic Dermatitis by Inhibiting T Cell and Keratinocyte Activation

Hyun-Su Lee,
Eun-Ju Choi,
Heeri Choi,
Kyung-Sik Lee,
Hye-Ran Kim,
Bo-Ra Na,
Min-Sung Kwon,
Gil-Saeng Jeong,
Hyun Gyu Choi,
Eun Young Choi

Published: December 10, 2015
https://doi.org/10.1371/journal.pone.0144521

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