The Risk of Tuberculosis Reinfection Soon after Cure of a First Disease Episode Is Extremely High in a Hyperendemic Community

Pieter Uys; Hilmarie Brand; Robin Warren; Gian van der Spuy; Eileen G. Hoal; Paul D van Helden

doi:10.1371/journal.pone.0144487

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Open Access

Peer-reviewed

Research Article

The Risk of Tuberculosis Reinfection Soon after Cure of a First Disease Episode Is Extremely High in a Hyperendemic Community

Pieter Uys ,

Contributed equally to this work with: Pieter Uys, Hilmarie Brand

* E-mail: pieter@edserve.co.za

Affiliations SACEMA, DST/NRF Centre of Excellence in Epidemiological Modelling and Analysis, University of Stellenbosch, Stellenbosch, Western Cape, South Africa, DST/NRF Centre of Excellence for Biomedical Tuberculosis Research / MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, Western Cape, South Africa
⨯
Hilmarie Brand ,

Contributed equally to this work with: Pieter Uys, Hilmarie Brand

Affiliation SACEMA, DST/NRF Centre of Excellence in Epidemiological Modelling and Analysis, University of Stellenbosch, Stellenbosch, Western Cape, South Africa
⨯
Robin Warren,

Affiliation DST/NRF Centre of Excellence for Biomedical Tuberculosis Research / MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, Western Cape, South Africa
⨯
Gian van der Spuy,

Affiliation DST/NRF Centre of Excellence for Biomedical Tuberculosis Research / MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, Western Cape, South Africa
⨯
Eileen G. Hoal,

Affiliation DST/NRF Centre of Excellence for Biomedical Tuberculosis Research / MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, Western Cape, South Africa
⨯
Paul D van Helden

Affiliation DST/NRF Centre of Excellence for Biomedical Tuberculosis Research / MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, Western Cape, South Africa
⨯

The Risk of Tuberculosis Reinfection Soon after Cure of a First Disease Episode Is Extremely High in a Hyperendemic Community

Pieter Uys,
Hilmarie Brand,
Robin Warren,
Gian van der Spuy,
Eileen G. Hoal,
Paul D van Helden

Published: December 9, 2015
https://doi.org/10.1371/journal.pone.0144487

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Tuberculosis
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Medical risk factors
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Recurrent diseases
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