Charge Shielding of PIP2 by Cations Regulates Enzyme Activity of Phospholipase C

Open Access

Peer-reviewed

Research Article

Charge Shielding of PIP₂ by Cations Regulates Enzyme Activity of Phospholipase C

Jong Bae Seo,

Affiliation Department of Physiology and Biophysics, University of Washington, Seattle, Washington, 98195, United States of America
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Seung-Ryoung Jung,

Affiliation Department of Physiology and Biophysics, University of Washington, Seattle, Washington, 98195, United States of America
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Weigang Huang,

Affiliation Division of Chemical Biology and Medicinal Chemistry, University of North Carolina, 120 Mason Farm Rd., Chapel Hill, NC 27599, United States of America
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Qisheng Zhang,

Affiliation Division of Chemical Biology and Medicinal Chemistry, University of North Carolina, 120 Mason Farm Rd., Chapel Hill, NC 27599, United States of America
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Duk-Su Koh

* E-mail: koh@uw.edu

Affiliation Department of Physiology and Biophysics, University of Washington, Seattle, Washington, 98195, United States of America
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Cations
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Neomycins
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Hydrolysis
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Ions
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Electrostatics
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Magnesium chloride
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Pipettes
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Recombinant proteins
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