Late Antiretroviral Therapy (ART) Initiation Is Associated with Long-Term Persistence of Systemic Inflammation and Metabolic Abnormalities

• Mathilde Ghislain ,

  * E-mail: mathilde.ghislain@inserm.fr

  Affiliation Inserm UMRS1018, CESP, Epidemiology of HIV and STI, Le Kremlin-Bicêtre, France

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• Jean-Philippe Bastard,

  Affiliations Tenon Hospital, AP-HP, Department of Biochemistry and Hormonology, Paris, France, Inserm UMRS 938, Centre de Recherche Saint-Antoine, Paris, France, Sorbonne Universities, UPMC, Institute of Cardiometabolism and Nutrition (ICAN), Paris, France

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• Laurence Meyer,

  Affiliations Inserm UMRS1018, CESP, Epidemiology of HIV and STI, Le Kremlin-Bicêtre, France, Paris-Sud university, Le Kremlin-Bicêtre, France, Bicêtre Hospital, AP-HP, Department of Public Health, Le Kremlin-Bicêtre, France

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• Jacqueline Capeau,

  Affiliations Tenon Hospital, AP-HP, Department of Biochemistry and Hormonology, Paris, France, Inserm UMRS 938, Centre de Recherche Saint-Antoine, Paris, France, Sorbonne Universities, UPMC, Institute of Cardiometabolism and Nutrition (ICAN), Paris, France

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• Soraya Fellahi,

  Affiliations Tenon Hospital, AP-HP, Department of Biochemistry and Hormonology, Paris, France, Inserm UMRS 938, Centre de Recherche Saint-Antoine, Paris, France, Sorbonne Universities, UPMC, Institute of Cardiometabolism and Nutrition (ICAN), Paris, France

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• Laurence Gérard,

  Affiliation Saint-Louis Hospital, AP-HP, Department of Clinic Immunopathology, Paris, France

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• Thierry May,

  Affiliation Teaching hospital of Nancy, Brabois Hospitals, Department of Infectious and Tropical Diseases, Vandoeuvre les Nancy, France

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• Anne Simon,

  Affiliation Pitié-Salpétrière Hospital, AP-HP, Department of Internal Medicine and Clinical Immunology, Paris, France

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• Corinne Vigouroux,

  Affiliations Inserm UMRS 938, Centre de Recherche Saint-Antoine, Paris, France, Sorbonne Universities, UPMC, Institute of Cardiometabolism and Nutrition (ICAN), Paris, France, Saint-Antoine Hospital, AP-HP, Common Laboratory of Biology and Molecular Genetics, Paris, France

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• Cécile Goujard,

  Affiliations Inserm UMRS1018, CESP, Epidemiology of HIV and STI, Le Kremlin-Bicêtre, France, Paris-Sud university, Le Kremlin-Bicêtre, France, Bicêtre Hospital, AP-HP, Department of Internal Medicine, Le Kremlin-Bicêtre, France

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• ANRS-COPANA Cohort Study Group

  ¶Membership of the ANRS-COPANA Cohort Study Group is provided in the Acknowledgments.

  Affiliation Inserm-ANRS, Paris, France

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