Cellular Hypertrophy and Increased Susceptibility to Spontaneous Calcium-Release of Rat Left Atrial Myocytes Due to Elevated Afterload

Haifei Zhang; Mark B. Cannell; Shang Jin Kim; Judy J. Watson; Ruth Norman; Sarah C. Calaghan; Clive H. Orchard; Andrew F. James

doi:10.1371/journal.pone.0144309

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Open Access

Peer-reviewed

Research Article

Cellular Hypertrophy and Increased Susceptibility to Spontaneous Calcium-Release of Rat Left Atrial Myocytes Due to Elevated Afterload

Haifei Zhang,

Affiliation Cardiovascular Research Laboratories, School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, BS8 1TD, United Kingdom
⨯
Mark B. Cannell,

Affiliation Cardiovascular Research Laboratories, School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, BS8 1TD, United Kingdom
⨯
Shang Jin Kim,

Current address: Department of Pharmacology and Toxicology, College of Veterinary Medicine, Chonbuk National University, 664–14 Deockjin-Dong, Jeonju-City, South Korea, 561–756

Affiliation Cardiovascular Research Laboratories, School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, BS8 1TD, United Kingdom
⨯
Judy J. Watson,

Affiliation Cardiovascular Research Laboratories, School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, BS8 1TD, United Kingdom
⨯
Ruth Norman,

Affiliation School of Biomedical Sciences, Garstang, University of Leeds, Leeds, LS2 9JT, United Kingdom
⨯
Sarah C. Calaghan,

Affiliation School of Biomedical Sciences, Garstang, University of Leeds, Leeds, LS2 9JT, United Kingdom
⨯
Clive H. Orchard,

Affiliation Cardiovascular Research Laboratories, School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, BS8 1TD, United Kingdom
⨯
Andrew F. James

* E-mail: a.james@bristol.ac.uk

Affiliation Cardiovascular Research Laboratories, School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, BS8 1TD, United Kingdom
⨯

Cellular Hypertrophy and Increased Susceptibility to Spontaneous Calcium-Release of Rat Left Atrial Myocytes Due to Elevated Afterload

Haifei Zhang,
Mark B. Cannell,
Shang Jin Kim,
Judy J. Watson,
Ruth Norman,
Sarah C. Calaghan,
Clive H. Orchard,
Andrew F. James

Published: December 29, 2015
https://doi.org/10.1371/journal.pone.0144309

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