The Synergistic Local Immunosuppressive Effects of Neural Stem Cells Expressing Indoleamine 2,3-Dioxygenase (IDO) in an Experimental Autoimmune Encephalomyelitis (EAE) Animal Model

Young Eun Lee; Jaeyeol An; Kee-Hang Lee; Sung Su Kim; Hye Jin Song; Heejang Pyeon; Hyun Nam; Kyeongjin Kang; Kyeung Min Joo

doi:10.1371/journal.pone.0144298

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Open Access

Peer-reviewed

Research Article

The Synergistic Local Immunosuppressive Effects of Neural Stem Cells Expressing Indoleamine 2,3-Dioxygenase (IDO) in an Experimental Autoimmune Encephalomyelitis (EAE) Animal Model

Young Eun Lee ,

Contributed equally to this work with: Young Eun Lee, Jaeyeol An

Affiliations Department of Health Science and Technology, Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Sungkyunkwan University, Seoul, Republic of Korea, Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
⨯
Jaeyeol An ,

Contributed equally to this work with: Young Eun Lee, Jaeyeol An

Affiliation Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
⨯
Kee-Hang Lee,

Affiliations Department of Health Science and Technology, Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Sungkyunkwan University, Seoul, Republic of Korea, Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
⨯
Sung Su Kim,

Affiliations Department of Health Science and Technology, Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Sungkyunkwan University, Seoul, Republic of Korea, Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
⨯
Hye Jin Song,

Affiliations Department of Anatomy and Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea, Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
⨯
Heejang Pyeon,

Affiliations Department of Anatomy and Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea, Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
⨯
Hyun Nam,

Affiliation Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
⨯
Kyeongjin Kang ,

* E-mail: kmjoo@skku.edu (KMJ); kangk@skku.edu (KK)

Affiliation Department of Anatomy and Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea
⨯
Kyeung Min Joo

* E-mail: kmjoo@skku.edu (KMJ); kangk@skku.edu (KK)

Affiliations Department of Health Science and Technology, Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Sungkyunkwan University, Seoul, Republic of Korea, Department of Anatomy and Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea, Samsung Biomedical Research Institute, Samsung Medical Center, Seoul, Republic of Korea
⨯

The Synergistic Local Immunosuppressive Effects of Neural Stem Cells Expressing Indoleamine 2,3-Dioxygenase (IDO) in an Experimental Autoimmune Encephalomyelitis (EAE) Animal Model

Young Eun Lee,
Jaeyeol An,
Kee-Hang Lee,
Sung Su Kim,
Hye Jin Song,
Heejang Pyeon,
Hyun Nam,
Kyeongjin Kang,
Kyeung Min Joo

Published: December 4, 2015
https://doi.org/10.1371/journal.pone.0144298

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