Mesenchymal Stem Cells Obtained from Synovial Fluid Mesenchymal Stem Cell-Derived Induced Pluripotent Stem Cells on a Matrigel Coating Exhibited Enhanced Proliferation and Differentiation Potential

Yu-Liang Zheng; Yang-Peng Sun; Hong Zhang; Wen-Jing Liu; Rui Jiang; Wen-Yu Li; You-Hua Zheng; Zhi-Guang Zhang

doi:10.1371/journal.pone.0144226

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Research Article

Mesenchymal Stem Cells Obtained from Synovial Fluid Mesenchymal Stem Cell-Derived Induced Pluripotent Stem Cells on a Matrigel Coating Exhibited Enhanced Proliferation and Differentiation Potential

Yu-Liang Zheng ,

Contributed equally to this work with: Yu-Liang Zheng, Yang-Peng Sun

Affiliations Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, Guangdong, P.R. China, Guangdong Second Traditional Chinese Medicine Hospital, Guangzhou, Guangdong, P.R. China
⨯
Yang-Peng Sun ,

Contributed equally to this work with: Yu-Liang Zheng, Yang-Peng Sun

* E-mail: kouqiangzzg@hotmail.com (ZZ); sunyp@mail2.sysu.edu.cn (YS)

Affiliation Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, Guangdong, P.R. China
⨯
Hong Zhang,

Affiliation Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, Guangdong, P.R. China
⨯
Wen-Jing Liu,

Affiliations Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, Guangdong, P.R. China, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, P.R. China
⨯
Rui Jiang,

Affiliation The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, P.R. China
⨯
Wen-Yu Li,

Affiliation The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, P.R. China
⨯
You-Hua Zheng,

Affiliation Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, Guangdong, P.R. China
⨯
Zhi-Guang Zhang

* E-mail: kouqiangzzg@hotmail.com (ZZ); sunyp@mail2.sysu.edu.cn (YS)

Affiliation Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, Guangdong, P.R. China
⨯

Mesenchymal Stem Cells Obtained from Synovial Fluid Mesenchymal Stem Cell-Derived Induced Pluripotent Stem Cells on a Matrigel Coating Exhibited Enhanced Proliferation and Differentiation Potential

Yu-Liang Zheng,
Yang-Peng Sun,
Hong Zhang,
Wen-Jing Liu,
Rui Jiang,
Wen-Yu Li,
You-Hua Zheng,
Zhi-Guang Zhang

Published: December 9, 2015
https://doi.org/10.1371/journal.pone.0144226

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Mesenchymal stem cells
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Induced pluripotent stem cells
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Cell differentiation
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Synovial fluid
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Transfection
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Immunofluorescence staining
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Cartilage
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