Regional Brain Glucose Hypometabolism in Young Women with Polycystic Ovary Syndrome: Possible Link to Mild Insulin Resistance

Christian-Alexandre Castellano; Jean-Patrice Baillargeon; Scott Nugent; Sébastien Tremblay; Mélanie Fortier; Hélène Imbeault; Julie Duval; Stephen C. Cunnane

doi:10.1371/journal.pone.0144116

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Open Access

Peer-reviewed

Research Article

Regional Brain Glucose Hypometabolism in Young Women with Polycystic Ovary Syndrome: Possible Link to Mild Insulin Resistance

Christian-Alexandre Castellano ,

* E-mail: Alexandre.Castellano@USherbrooke.ca

Affiliations Research Centre on Aging, Sherbrooke University Geriatrics Institute, Sherbrooke, QC, Canada, Department of Pharmacology and Physiology, Université de Sherbrooke, Sherbrooke, QC, Canada
⨯
Jean-Patrice Baillargeon,

Affiliations Department of Medicine, Université de Sherbrooke, Sherbrooke, QC, Canada, Research Center of the Centre hospitalier universitaire de Sherbrooke, Sherbrooke, QC, Canada
⨯
Scott Nugent,

Affiliations Research Centre on Aging, Sherbrooke University Geriatrics Institute, Sherbrooke, QC, Canada, Department of Pharmacology and Physiology, Université de Sherbrooke, Sherbrooke, QC, Canada
⨯
Sébastien Tremblay,

Affiliations Sherbrooke Molecular Imaging Center, Université de Sherbrooke, Sherbrooke, QC, Canada, Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, QC, Canada
⨯
Mélanie Fortier,

Affiliation Research Centre on Aging, Sherbrooke University Geriatrics Institute, Sherbrooke, QC, Canada
⨯
Hélène Imbeault,

Affiliation Health and Social Sciences Center–Sherbrooke University Geriatrics Institute, Sherbrooke, QC, Canada
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Julie Duval,

Affiliations Health and Social Sciences Center–Sherbrooke University Geriatrics Institute, Sherbrooke, QC, Canada, Department of Neurology, Centre hospitalier universitaire de Sherbrooke, Sherbrooke, QC, Canada
⨯
Stephen C. Cunnane

Affiliations Research Centre on Aging, Sherbrooke University Geriatrics Institute, Sherbrooke, QC, Canada, Department of Pharmacology and Physiology, Université de Sherbrooke, Sherbrooke, QC, Canada, Department of Medicine, Université de Sherbrooke, Sherbrooke, QC, Canada
⨯

Regional Brain Glucose Hypometabolism in Young Women with Polycystic Ovary Syndrome: Possible Link to Mild Insulin Resistance

Christian-Alexandre Castellano,
Jean-Patrice Baillargeon,
Scott Nugent,
Sébastien Tremblay,
Mélanie Fortier,
Hélène Imbeault,
Julie Duval,
Stephen C. Cunnane

Published: December 9, 2015
https://doi.org/10.1371/journal.pone.0144116

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Polycystic ovary syndrome
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Glucose
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Insulin resistance
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Glucose metabolism
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Cerebral metabolic rate assay
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Insulin
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