Geometrical Frustration in Interleukin-33 Decouples the Dynamics of the Functional Element from the Folding Transition State Ensemble

• Kaitlin M. Fisher,

  Affiliation Department of Chemistry and Biochemistry, University of California at San Diego (UCSD), La Jolla, CA, United States of America

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• Ellinor Haglund,

  Affiliations Center for Theoretical Biological Physics (CTBP) and Department of Physics, University of California at San Diego (UCSD), La Jolla, CA, United States of America, Center for Theoretical Biological Physics (CTBP) and Department of Physics and Astronomy, Chemistry and Biochemistry and Cell Biology, Rice University, Houston, TX, United States of America

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• Jeffrey K. Noel,

  Affiliation Center for Theoretical Biological Physics (CTBP) and Department of Physics and Astronomy, Chemistry and Biochemistry and Cell Biology, Rice University, Houston, TX, United States of America

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• Kendra L. Hailey,

  Affiliation Department of Chemistry and Biochemistry, University of California at San Diego (UCSD), La Jolla, CA, United States of America

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• José N. Onuchic,

  Affiliation Center for Theoretical Biological Physics (CTBP) and Department of Physics and Astronomy, Chemistry and Biochemistry and Cell Biology, Rice University, Houston, TX, United States of America

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• Patricia A. Jennings

  * E-mail: pajennings@ucsd.edu

  Affiliation Department of Chemistry and Biochemistry, University of California at San Diego (UCSD), La Jolla, CA, United States of America

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