BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transgenic Mouse Model of Papillary Thyroid Carcinoma

Dagmara Rusinek; Michal Swierniak; Ewa Chmielik; Monika Kowal; Malgorzata Kowalska; Renata Cyplinska; Agnieszka Czarniecka; Wojciech Piglowski; Joanna Korfanty; Mykola Chekan; Jolanta Krajewska; Sylwia Szpak-Ulczok; Michal Jarzab; Wieslawa Widlak; Barbara Jarzab

doi:10.1371/journal.pone.0143688

Loading metrics

Open Access

Peer-reviewed

Research Article

BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transgenic Mouse Model of Papillary Thyroid Carcinoma

Dagmara Rusinek ,

* E-mail: Dagmara.Rusinek@io.gliwice.pl

Affiliation Department of Nuclear Medicine and Endocrine Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯
Michal Swierniak,

Affiliations Department of Nuclear Medicine and Endocrine Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland, Genomic Medicine, Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland
⨯
Ewa Chmielik,

Affiliation Department of Tumor Pathology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯
Monika Kowal,

Affiliation Department of Nuclear Medicine and Endocrine Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯
Malgorzata Kowalska,

Affiliation Department of Nuclear Medicine and Endocrine Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯
Renata Cyplinska,

Affiliation Department of Nuclear Medicine and Endocrine Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯
Agnieszka Czarniecka,

Affiliation Department of Oncological and Reconstructive Surgery, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯
Wojciech Piglowski,

Affiliation Center for Translational Research and Molecular Biology of Cancer, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯
Joanna Korfanty,

Affiliation Center for Translational Research and Molecular Biology of Cancer, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯
Mykola Chekan,

Affiliation Department of Tumor Pathology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯
Jolanta Krajewska,

Affiliation Department of Nuclear Medicine and Endocrine Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯
Sylwia Szpak-Ulczok,

Affiliation Department of Nuclear Medicine and Endocrine Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯
Michal Jarzab,

Affiliation III Department of Radiotherapy and Chemotherapy, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯
Wieslawa Widlak,

Affiliations III Department of Radiotherapy and Chemotherapy, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland, II Department of Radiotherapy and Chemotherapy, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯
Barbara Jarzab

Affiliation Department of Nuclear Medicine and Endocrine Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland
⨯

BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transgenic Mouse Model of Papillary Thyroid Carcinoma

Dagmara Rusinek,
Michal Swierniak,
Ewa Chmielik,
Monika Kowal,
Malgorzata Kowalska,
Renata Cyplinska,
Agnieszka Czarniecka,
Wojciech Piglowski,
Joanna Korfanty,
Mykola Chekan

Published: December 1, 2015
https://doi.org/10.1371/journal.pone.0143688

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Thyroid
Is the Subject Area "Thyroid" applicable to this article?

Thanks for your feedback.
Thyroid carcinoma
Is the Subject Area "Thyroid carcinoma" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Genetically modified animals
Is the Subject Area "Genetically modified animals" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Mammalian genomics
Is the Subject Area "Mammalian genomics" applicable to this article?

Thanks for your feedback.
Microarrays
Is the Subject Area "Microarrays" applicable to this article?

Thanks for your feedback.
Cancer genomics
Is the Subject Area "Cancer genomics" applicable to this article?

Thanks for your feedback.