The Synthetic Antimicrobial Peptide 19-2.5 Interacts with Heparanase and Heparan Sulfate in Murine and Human Sepsis

• Lukas Martin,

  Affiliation Department of Intensive Care and Intermediate Care, University Hospital RWTH, Aachen, Germany

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• Rebecca De Santis,

  Affiliation Department of Intensive Care and Intermediate Care, University Hospital RWTH, Aachen, Germany

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• Patrick Koczera,

  Affiliation Department of Intensive Care and Intermediate Care, University Hospital RWTH, Aachen, Germany

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• Nadine Simons,

  Affiliation Department of Intensive Care and Intermediate Care, University Hospital RWTH, Aachen, Germany

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• Hajo Haase,

  Affiliation Department of Food Chemistry and Toxicology, Berlin Institute of Technology, Berlin, Germany

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• Lena Heinbockel,

  Affiliation Division of Biophysics, Forschungszentrum Borstel, Borstel, Germany

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• Klaus Brandenburg,

  Affiliation Division of Biophysics, Forschungszentrum Borstel, Borstel, Germany

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• Gernot Marx,

  Affiliation Department of Intensive Care and Intermediate Care, University Hospital RWTH, Aachen, Germany

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• Tobias Schuerholz

  * E-mail: tschuerholz@ukaachen.de

  Affiliation Department of Intensive Care and Intermediate Care, University Hospital RWTH, Aachen, Germany

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