Tacrolimus Induces Insulin Resistance and Increases the Glucose Absorption in the Jejunum: A Potential Mechanism of the Diabetogenic Effects

Zhiwei Li; Fei Sun; Yaohui Zhang; Hao Chen; Ningning He; Hui Chen; Penghong Song; Yan Wang; Sheng Yan; Shusen Zheng

doi:10.1371/journal.pone.0143405

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Open Access

Peer-reviewed

Research Article

Tacrolimus Induces Insulin Resistance and Increases the Glucose Absorption in the Jejunum: A Potential Mechanism of the Diabetogenic Effects

Zhiwei Li ,

Contributed equally to this work with: Zhiwei Li, Fei Sun

Affiliation Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
⨯
Fei Sun ,

Contributed equally to this work with: Zhiwei Li, Fei Sun

Affiliation Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
⨯
Yaohui Zhang,

Affiliation Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
⨯
Hao Chen,

Affiliation Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
⨯
Ningning He,

Affiliation Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
⨯
Hui Chen,

Affiliation Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
⨯
Penghong Song,

Affiliation Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
⨯
Yan Wang,

Affiliation Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
⨯
Sheng Yan,

Affiliation Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
⨯
Shusen Zheng

* E-mail: shusenzheng@zju.edu.cn

Affiliations Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China
⨯

Tacrolimus Induces Insulin Resistance and Increases the Glucose Absorption in the Jejunum: A Potential Mechanism of the Diabetogenic Effects

Zhiwei Li,
Fei Sun,
Yaohui Zhang,
Hao Chen,
Ningning He,
Hui Chen,
Penghong Song,
Yan Wang,
Sheng Yan,
Shusen Zheng

Published: November 23, 2015
https://doi.org/10.1371/journal.pone.0143405

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