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Open Access

Peer-reviewed

Research Article

Cumulus Cells Block Oocyte Meiotic Resumption via Gap Junctions in Cumulus Oocyte Complexes Subjected to DNA Double-Strand Breaks

Ming-Hong Sun,

Affiliations College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, Shandong, China, Institute of Reproductive Science, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, Shandong, China
⨯
Jie Zheng,

Affiliation College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, Shandong, China
⨯
Feng-Yun Xie,

Affiliation College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, Shandong, China
⨯
Wei Shen,

Affiliations College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, Shandong, China, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, Qingdao Agricultural University, Qingdao, Shandong, China, Institute of Reproductive Science, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, Shandong, China
⨯
Shen Yin,

Affiliations College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, Shandong, China, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, Qingdao Agricultural University, Qingdao, Shandong, China, Institute of Reproductive Science, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, Shandong, China
⨯
Jun-Yu Ma

* E-mail: jyma@qau.edu.cn

Affiliations College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, Shandong, China, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, Qingdao Agricultural University, Qingdao, Shandong, China, Institute of Reproductive Science, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, Shandong, China
⨯

Cumulus Cells Block Oocyte Meiotic Resumption via Gap Junctions in Cumulus Oocyte Complexes Subjected to DNA Double-Strand Breaks

Ming-Hong Sun,
Jie Zheng,
Feng-Yun Xie,
Wei Shen,
Shen Yin,
Jun-Yu Ma

x

Published: November 17, 2015
https://doi.org/10.1371/journal.pone.0143223

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Oocytes
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DNA damage
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Gap junctions
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Meiosis
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Zona pellucida
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DNA
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Mammalian genomics
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Gene expression
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