Treatment Planning and Delivery of Whole Brain Irradiation with Hippocampal Avoidance in Rats

C. K. Cramer; S. W. Yoon; M. Reinsvold; K. M. Joo; H. Norris; R. C. Hood; J. D. Adamson; R. C. Klein; D. G. Kirsch; M. Oldham

doi:10.1371/journal.pone.0143208

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Open Access

Peer-reviewed

Research Article

Treatment Planning and Delivery of Whole Brain Irradiation with Hippocampal Avoidance in Rats

C. K. Cramer ,

* E-mail: Christina.Cramer@duke.edu

Affiliation Department of Radiation Oncology, Duke University Medical Center, Durham, NC, United States of America
⨯
S. W. Yoon,

Affiliation Department of Radiation Oncology, Duke University Medical Center, Durham, NC, United States of America
⨯
M. Reinsvold,

Affiliation Department of Radiation Oncology, Duke University Medical Center, Durham, NC, United States of America
⨯
K. M. Joo,

Affiliations Department of Radiation Oncology, Duke University Medical Center, Durham, NC, United States of America, Department of Anatomy and Cell Biology, Sungkyunkwan University School of Medicine, Seoul, South Korea
⨯
H. Norris,

Affiliation Department of Radiation Oncology, Duke University Medical Center, Durham, NC, United States of America
⨯
R. C. Hood,

Affiliation Department of Radiation Oncology, Duke University Medical Center, Durham, NC, United States of America
⨯
J. D. Adamson,

Affiliation Department of Radiation Oncology, Duke University Medical Center, Durham, NC, United States of America
⨯
R. C. Klein,

Affiliations Department of Psychiatry, Durham VA, Durham, NC, United States of America, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States of America
⨯
D. G. Kirsch ,

¶‡ These authors are co-senior authors on this work.

Affiliations Department of Radiation Oncology, Duke University Medical Center, Durham, NC, United States of America, Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, NC, United States of America
⨯
M. Oldham

¶‡ These authors are co-senior authors on this work.

Affiliation Department of Radiation Oncology, Duke University Medical Center, Durham, NC, United States of America
⨯

Treatment Planning and Delivery of Whole Brain Irradiation with Hippocampal Avoidance in Rats

C. K. Cramer,
S. W. Yoon,
M. Reinsvold,
K. M. Joo,
H. Norris,
R. C. Hood,
J. D. Adamson,
R. C. Klein,
D. G. Kirsch,
M. Oldham

Published: December 4, 2015
https://doi.org/10.1371/journal.pone.0143208

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Radiation therapy
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Rats
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Brain damage
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Wistar rats
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