Transforming Growth Factor TGFβ Increases Levels of Microtubule-Associated Protein MAP1S and Autophagy Flux in Pancreatic Ductal Adenocarcinomas

Kun Song; Wei Hu; Fei Yue; Jing Zou; Wenjiao Li; Qi Chen; Qizhi Yao; Weijia Sun; Leyuan Liu

doi:10.1371/journal.pone.0143150

Loading metrics

Open Access

Peer-reviewed

Research Article

Transforming Growth Factor TGFβ Increases Levels of Microtubule-Associated Protein MAP1S and Autophagy Flux in Pancreatic Ductal Adenocarcinomas

Kun Song,

Affiliations Department of General Surgery, Xiangya Hospital, Central South University, Xiangya Road 87, 410008, Changsha, Hunan Province, China, Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, Texas, United States of America
⨯
Wei Hu,

Affiliation The First People’s Hospital, Lian Yungang City, Jiangsu Province, China
⨯
Fei Yue,

Affiliation Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, Texas, United States of America
⨯
Jing Zou,

Affiliation Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, Texas, United States of America
⨯
Wenjiao Li,

Affiliation Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, Texas, United States of America
⨯
Qi Chen,

Affiliation Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, Texas, United States of America
⨯
Qizhi Yao,

Affiliation Department of Surgery, Molecular Surgeon Research Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, United States of America
⨯
Weijia Sun ,

* E-mail: sunweijia2009@126.com (WS); lliu@ibt.tamhsc.edu (LL)

Affiliation Department of General Surgery, Xiangya Hospital, Central South University, Xiangya Road 87, 410008, Changsha, Hunan Province, China
⨯
Leyuan Liu

* E-mail: sunweijia2009@126.com (WS); lliu@ibt.tamhsc.edu (LL)

Affiliations Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, Texas, United States of America, Department of Molecular and Cellular Medicine, College of Medicine, Texas A&M Health Science Center, College Station, Texas, United States of America
⨯

Transforming Growth Factor TGFβ Increases Levels of Microtubule-Associated Protein MAP1S and Autophagy Flux in Pancreatic Ductal Adenocarcinomas

Kun Song,
Wei Hu,
Fei Yue,
Jing Zou,
Wenjiao Li,
Qi Chen,
Qizhi Yao,
Weijia Sun,
Leyuan Liu

Published: November 16, 2015
https://doi.org/10.1371/journal.pone.0143150

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Autophagic cell death
Is the Subject Area "Autophagic cell death" applicable to this article?

Thanks for your feedback.
Pancreatic cancer
Is the Subject Area "Pancreatic cancer" applicable to this article?

Thanks for your feedback.
Adenocarcinoma
Is the Subject Area "Adenocarcinoma" applicable to this article?

Thanks for your feedback.
Hepatocellular carcinoma
Is the Subject Area "Hepatocellular carcinoma" applicable to this article?

Thanks for your feedback.
Prostate cancer
Is the Subject Area "Prostate cancer" applicable to this article?

Thanks for your feedback.
Carcinogenesis
Is the Subject Area "Carcinogenesis" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Immunostaining
Is the Subject Area "Immunostaining" applicable to this article?

Thanks for your feedback.