IL4I1 Is a Novel Regulator of M2 Macrophage Polarization That Can Inhibit T Cell Activation via L-Tryptophan and Arginine Depletion and IL-10 Production

• Yinpu Yue,

  Affiliation Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, P. R. China

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• Wei Huang,

  Affiliation Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, P. R. China

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• Jingjing Liang,

  Affiliation Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, P. R. China

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• Jing Guo,

  Affiliation Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, P. R. China

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• Jian Ji,

  Affiliation College of Animal Sciences, Key Laboratory of Animal Molecular Nutrition of the Ministry of Education, Zhejiang University, Hangzhou, P. R. China

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• Yunliang Yao,

  Affiliations Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, P. R. China, Department of Microbiology and Immunology, Medical School of Huzhou Teachers College, Huzhou, P. R. China

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• Mingzhu Zheng,

  Affiliation Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, P. R. China

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• Zhijian Cai,

  Affiliation Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, P. R. China

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• Linrong Lu ,

  * E-mail: jlwang@zju.edu.cn (JW); lu_linrong@zju.edu.cn (LL)

  Affiliations Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, P. R. China, Program in Molecular and Cellular Biology, Zhejiang University School of Medicine, Hangzhou, P. R. China

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• Jianli Wang

  * E-mail: jlwang@zju.edu.cn (JW); lu_linrong@zju.edu.cn (LL)

  Affiliation Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, P. R. China

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